Enhanced Expression of Neuron‐specific Enolase (NSE) in Pyothorax‐associated Lymphoma (PAL)

Pyothorax‐associated lymphoma (PAL) is a B‐cell lymphoma of mostly large cell type developing in the pleural cavity of patients with long‐standing pyothorax. Neuron‐specific enolase (NSE) is an enolase comprising γ subunit and is located at high levels in neuronal and neuroendocrine cells, together...

Ausführliche Beschreibung

Gespeichert in:
Bibliographische Detailangaben
Veröffentlicht in:Cancer science 2002-04, Vol.93 (4), p.411-416
Hauptverfasser: Nakatsuka, Shin‐ichi, Nishiu, Mieko, Tomita, Yasuhiko, Miwa, Hideaki, Takakuwa, Tetsuya, Luchi, Keiji, Yamamoto, Satoru, Aozasa, Katsuyuki
Format: Artikel
Sprache:eng
Schlagworte:
Online-Zugang:Volltext
Tags: Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
container_end_page 416
container_issue 4
container_start_page 411
container_title Cancer science
container_volume 93
creator Nakatsuka, Shin‐ichi
Nishiu, Mieko
Tomita, Yasuhiko
Miwa, Hideaki
Takakuwa, Tetsuya
Luchi, Keiji
Yamamoto, Satoru
Aozasa, Katsuyuki
description Pyothorax‐associated lymphoma (PAL) is a B‐cell lymphoma of mostly large cell type developing in the pleural cavity of patients with long‐standing pyothorax. Neuron‐specific enolase (NSE) is an enolase comprising γ subunit and is located at high levels in neuronal and neuroendocrine cells, together with their neoplasias. Expression of NSE at protein and mRNA levels was examined in PAL and other types (non‐PAL) of non‐Hodgkin's lymphomas. In PAL, serum levels of NSE were elevated (5.32 to 168.0, mean 42.6 ng/ml) and tended to decrease after incisional biopsy followed by chemotherapy (2.38 to 195.5, mean 34.1 ng/ml). Two cell lines established from two cases of PAL produced and secreted NSE in the culture medium. Immunohistochemistry revealed that the positive rate for NSE staining in PAL (10 of 14 cases, 71.4%) was significantly higher than that in non‐PAL cases (6 of 38 cases, 15.8%) (P
doi_str_mv 10.1111/j.1349-7006.2002.tb01272.x
format Article
fullrecord <record><control><sourceid>proquest_pubme</sourceid><recordid>TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_5927012</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><sourcerecordid>71648341</sourcerecordid><originalsourceid>FETCH-LOGICAL-c5861-68936e83812264579ad6527885b9b61aeb18d69e169e2169c576cf18d67986a83</originalsourceid><addsrcrecordid>eNqVkd-K1DAUxoO4uOPqK0hRlN2L1iRt_tQLYRi6qzCsC-p1SDOpk6FNukmrM3c-gs_ok2zKlh31zkByIOd3Ps45HwAvEcxQPG93GcqLMmUQ0gxDiLOhhggznO0fgcVD6jFYwBLBlEACT8HTEHYQIgYpfgJOESo5YSVaAFHZrbRKb5Jq33sdgnE2cU1yrUfv7O-fv0KvlWmMSirrWhl0cn79ubpIjE1uDm7YOi_3kZIhOGXkEHXWh67fuk4m5zfL9cUzcNLINujnczwDXy-rL6sP6frT1cfVcp0qwilKKS9zqnnOEca0iK3JDSWYcU7qsqZI6hrxDS01ihfHRxFGVTP9sZJTyfMz8P5etx_rTm-UtoOXrei96aQ_CCeN-DtjzVZ8c98FKTGL24sCb2YB725HHQbRmaB020qr3RgEQ7TgeYEi-OofcOdGb-NwAhdxxZgTTCL17p5S3oXgdfPQCoJiclHsxGSVmKwSk4tidlHsY_GLP4c5ls62ReD1DMigZNv4aKEJRy7njLEcH7fyw7T68B8tiNWyKhDK7wBobLnk</addsrcrecordid><sourcetype>Open Access Repository</sourcetype><iscdi>true</iscdi><recordtype>article</recordtype><pqid>2400128525</pqid></control><display><type>article</type><title>Enhanced Expression of Neuron‐specific Enolase (NSE) in Pyothorax‐associated Lymphoma (PAL)</title><source>MEDLINE</source><source>IngentaConnect Free/Open Access Journals</source><source>EZB-FREE-00999 freely available EZB journals</source><source>Wiley Online Library All Journals</source><source>PubMed Central</source><creator>Nakatsuka, Shin‐ichi ; Nishiu, Mieko ; Tomita, Yasuhiko ; Miwa, Hideaki ; Takakuwa, Tetsuya ; Luchi, Keiji ; Yamamoto, Satoru ; Aozasa, Katsuyuki</creator><creatorcontrib>Nakatsuka, Shin‐ichi ; Nishiu, Mieko ; Tomita, Yasuhiko ; Miwa, Hideaki ; Takakuwa, Tetsuya ; Luchi, Keiji ; Yamamoto, Satoru ; Aozasa, Katsuyuki</creatorcontrib><description>Pyothorax‐associated lymphoma (PAL) is a B‐cell lymphoma of mostly large cell type developing in the pleural cavity of patients with long‐standing pyothorax. Neuron‐specific enolase (NSE) is an enolase comprising γ subunit and is located at high levels in neuronal and neuroendocrine cells, together with their neoplasias. Expression of NSE at protein and mRNA levels was examined in PAL and other types (non‐PAL) of non‐Hodgkin's lymphomas. In PAL, serum levels of NSE were elevated (5.32 to 168.0, mean 42.6 ng/ml) and tended to decrease after incisional biopsy followed by chemotherapy (2.38 to 195.5, mean 34.1 ng/ml). Two cell lines established from two cases of PAL produced and secreted NSE in the culture medium. Immunohistochemistry revealed that the positive rate for NSE staining in PAL (10 of 14 cases, 71.4%) was significantly higher than that in non‐PAL cases (6 of 38 cases, 15.8%) (P&lt;0.01). RT‐PCR analysis showed that the expression levels of NSE mRNA in two cell lines and a biopsy sample from PAL were rather similar to those of the control samples from non‐neoplastic lymph nodes. These findings suggest the posttranscriptional regulation of NSE in PAL. Thus, an elevation of serum NSE level in patients with chronic pyothorax may be an indicator of PAL development.</description><identifier>ISSN: 0910-5050</identifier><identifier>ISSN: 1347-9032</identifier><identifier>EISSN: 1349-7006</identifier><identifier>EISSN: 1876-4673</identifier><identifier>DOI: 10.1111/j.1349-7006.2002.tb01272.x</identifier><identifier>PMID: 11985791</identifier><identifier>CODEN: GANNA2</identifier><language>eng</language><publisher>Oxford, UK: Blackwell Publishing Ltd</publisher><subject>Adolescent ; Adult ; Aged ; Biological and medical sciences ; Biopsy ; Cell culture ; Cell Line, Tumor ; Chemotherapy ; Drug Therapy ; Empyema, Pleural - metabolism ; Female ; Gene expression ; Gene Expression Regulation, Enzymologic ; Gene Expression Regulation, Neoplastic ; Hematologic and hematopoietic diseases ; Humans ; Immunohistochemistry ; Leukemias. Malignant lymphomas. Malignant reticulosis. Myelofibrosis ; Lymph nodes ; Lymphoma ; Lymphoma - blood ; Lymphoma - enzymology ; Lymphoma, B-Cell - blood ; Lymphoma, B-Cell - enzymology ; Lymphoma, Non-Hodgkin - blood ; Lymphoma, Non-Hodgkin - enzymology ; Male ; Medical sciences ; Middle Aged ; mRNA ; Neuron‐specific enolase ; Phosphopyruvate hydratase ; Phosphopyruvate Hydratase - blood ; Pleural cavity ; Post-transcription ; Pyothorax‐associated lymphoma ; Quantitative reverse transcription PCR ; Reverse Transcriptase Polymerase Chain Reaction ; RNA - metabolism ; RNA, Messenger - metabolism ; Serum levels</subject><ispartof>Cancer science, 2002-04, Vol.93 (4), p.411-416</ispartof><rights>2002 INIST-CNRS</rights><rights>Copyright John Wiley &amp; Sons, Inc. Apr 2002</rights><lds50>peer_reviewed</lds50><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c5861-68936e83812264579ad6527885b9b61aeb18d69e169e2169c576cf18d67986a83</citedby><cites>FETCH-LOGICAL-c5861-68936e83812264579ad6527885b9b61aeb18d69e169e2169c576cf18d67986a83</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://www.ncbi.nlm.nih.gov/pmc/articles/PMC5927012/pdf/$$EPDF$$P50$$Gpubmedcentral$$Hfree_for_read</linktopdf><linktohtml>$$Uhttps://www.ncbi.nlm.nih.gov/pmc/articles/PMC5927012/$$EHTML$$P50$$Gpubmedcentral$$Hfree_for_read</linktohtml><link.rule.ids>230,314,727,780,784,885,1416,27923,27924,45573,45574,53790,53792</link.rule.ids><backlink>$$Uhttp://pascal-francis.inist.fr/vibad/index.php?action=getRecordDetail&amp;idt=13877732$$DView record in Pascal Francis$$Hfree_for_read</backlink><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/11985791$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Nakatsuka, Shin‐ichi</creatorcontrib><creatorcontrib>Nishiu, Mieko</creatorcontrib><creatorcontrib>Tomita, Yasuhiko</creatorcontrib><creatorcontrib>Miwa, Hideaki</creatorcontrib><creatorcontrib>Takakuwa, Tetsuya</creatorcontrib><creatorcontrib>Luchi, Keiji</creatorcontrib><creatorcontrib>Yamamoto, Satoru</creatorcontrib><creatorcontrib>Aozasa, Katsuyuki</creatorcontrib><title>Enhanced Expression of Neuron‐specific Enolase (NSE) in Pyothorax‐associated Lymphoma (PAL)</title><title>Cancer science</title><addtitle>Jpn J Cancer Res</addtitle><description>Pyothorax‐associated lymphoma (PAL) is a B‐cell lymphoma of mostly large cell type developing in the pleural cavity of patients with long‐standing pyothorax. Neuron‐specific enolase (NSE) is an enolase comprising γ subunit and is located at high levels in neuronal and neuroendocrine cells, together with their neoplasias. Expression of NSE at protein and mRNA levels was examined in PAL and other types (non‐PAL) of non‐Hodgkin's lymphomas. In PAL, serum levels of NSE were elevated (5.32 to 168.0, mean 42.6 ng/ml) and tended to decrease after incisional biopsy followed by chemotherapy (2.38 to 195.5, mean 34.1 ng/ml). Two cell lines established from two cases of PAL produced and secreted NSE in the culture medium. Immunohistochemistry revealed that the positive rate for NSE staining in PAL (10 of 14 cases, 71.4%) was significantly higher than that in non‐PAL cases (6 of 38 cases, 15.8%) (P&lt;0.01). RT‐PCR analysis showed that the expression levels of NSE mRNA in two cell lines and a biopsy sample from PAL were rather similar to those of the control samples from non‐neoplastic lymph nodes. These findings suggest the posttranscriptional regulation of NSE in PAL. Thus, an elevation of serum NSE level in patients with chronic pyothorax may be an indicator of PAL development.</description><subject>Adolescent</subject><subject>Adult</subject><subject>Aged</subject><subject>Biological and medical sciences</subject><subject>Biopsy</subject><subject>Cell culture</subject><subject>Cell Line, Tumor</subject><subject>Chemotherapy</subject><subject>Drug Therapy</subject><subject>Empyema, Pleural - metabolism</subject><subject>Female</subject><subject>Gene expression</subject><subject>Gene Expression Regulation, Enzymologic</subject><subject>Gene Expression Regulation, Neoplastic</subject><subject>Hematologic and hematopoietic diseases</subject><subject>Humans</subject><subject>Immunohistochemistry</subject><subject>Leukemias. Malignant lymphomas. Malignant reticulosis. Myelofibrosis</subject><subject>Lymph nodes</subject><subject>Lymphoma</subject><subject>Lymphoma - blood</subject><subject>Lymphoma - enzymology</subject><subject>Lymphoma, B-Cell - blood</subject><subject>Lymphoma, B-Cell - enzymology</subject><subject>Lymphoma, Non-Hodgkin - blood</subject><subject>Lymphoma, Non-Hodgkin - enzymology</subject><subject>Male</subject><subject>Medical sciences</subject><subject>Middle Aged</subject><subject>mRNA</subject><subject>Neuron‐specific enolase</subject><subject>Phosphopyruvate hydratase</subject><subject>Phosphopyruvate Hydratase - blood</subject><subject>Pleural cavity</subject><subject>Post-transcription</subject><subject>Pyothorax‐associated lymphoma</subject><subject>Quantitative reverse transcription PCR</subject><subject>Reverse Transcriptase Polymerase Chain Reaction</subject><subject>RNA - metabolism</subject><subject>RNA, Messenger - metabolism</subject><subject>Serum levels</subject><issn>0910-5050</issn><issn>1347-9032</issn><issn>1349-7006</issn><issn>1876-4673</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2002</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><sourceid>ABUWG</sourceid><sourceid>AFKRA</sourceid><sourceid>AZQEC</sourceid><sourceid>BENPR</sourceid><sourceid>CCPQU</sourceid><sourceid>DWQXO</sourceid><sourceid>GNUQQ</sourceid><recordid>eNqVkd-K1DAUxoO4uOPqK0hRlN2L1iRt_tQLYRi6qzCsC-p1SDOpk6FNukmrM3c-gs_ok2zKlh31zkByIOd3Ps45HwAvEcxQPG93GcqLMmUQ0gxDiLOhhggznO0fgcVD6jFYwBLBlEACT8HTEHYQIgYpfgJOESo5YSVaAFHZrbRKb5Jq33sdgnE2cU1yrUfv7O-fv0KvlWmMSirrWhl0cn79ubpIjE1uDm7YOi_3kZIhOGXkEHXWh67fuk4m5zfL9cUzcNLINujnczwDXy-rL6sP6frT1cfVcp0qwilKKS9zqnnOEca0iK3JDSWYcU7qsqZI6hrxDS01ihfHRxFGVTP9sZJTyfMz8P5etx_rTm-UtoOXrei96aQ_CCeN-DtjzVZ8c98FKTGL24sCb2YB725HHQbRmaB020qr3RgEQ7TgeYEi-OofcOdGb-NwAhdxxZgTTCL17p5S3oXgdfPQCoJiclHsxGSVmKwSk4tidlHsY_GLP4c5ls62ReD1DMigZNv4aKEJRy7njLEcH7fyw7T68B8tiNWyKhDK7wBobLnk</recordid><startdate>200204</startdate><enddate>200204</enddate><creator>Nakatsuka, Shin‐ichi</creator><creator>Nishiu, Mieko</creator><creator>Tomita, Yasuhiko</creator><creator>Miwa, Hideaki</creator><creator>Takakuwa, Tetsuya</creator><creator>Luchi, Keiji</creator><creator>Yamamoto, Satoru</creator><creator>Aozasa, Katsuyuki</creator><general>Blackwell Publishing Ltd</general><general>Japanese Cancer Association</general><general>John Wiley &amp; Sons, Inc</general><scope>IQODW</scope><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>8FE</scope><scope>8FH</scope><scope>ABUWG</scope><scope>AFKRA</scope><scope>AZQEC</scope><scope>BBNVY</scope><scope>BENPR</scope><scope>BHPHI</scope><scope>CCPQU</scope><scope>DWQXO</scope><scope>GNUQQ</scope><scope>HCIFZ</scope><scope>LK8</scope><scope>M7P</scope><scope>PIMPY</scope><scope>PQEST</scope><scope>PQQKQ</scope><scope>PQUKI</scope><scope>PRINS</scope><scope>7X8</scope><scope>5PM</scope></search><sort><creationdate>200204</creationdate><title>Enhanced Expression of Neuron‐specific Enolase (NSE) in Pyothorax‐associated Lymphoma (PAL)</title><author>Nakatsuka, Shin‐ichi ; Nishiu, Mieko ; Tomita, Yasuhiko ; Miwa, Hideaki ; Takakuwa, Tetsuya ; Luchi, Keiji ; Yamamoto, Satoru ; Aozasa, Katsuyuki</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c5861-68936e83812264579ad6527885b9b61aeb18d69e169e2169c576cf18d67986a83</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2002</creationdate><topic>Adolescent</topic><topic>Adult</topic><topic>Aged</topic><topic>Biological and medical sciences</topic><topic>Biopsy</topic><topic>Cell culture</topic><topic>Cell Line, Tumor</topic><topic>Chemotherapy</topic><topic>Drug Therapy</topic><topic>Empyema, Pleural - metabolism</topic><topic>Female</topic><topic>Gene expression</topic><topic>Gene Expression Regulation, Enzymologic</topic><topic>Gene Expression Regulation, Neoplastic</topic><topic>Hematologic and hematopoietic diseases</topic><topic>Humans</topic><topic>Immunohistochemistry</topic><topic>Leukemias. Malignant lymphomas. Malignant reticulosis. Myelofibrosis</topic><topic>Lymph nodes</topic><topic>Lymphoma</topic><topic>Lymphoma - blood</topic><topic>Lymphoma - enzymology</topic><topic>Lymphoma, B-Cell - blood</topic><topic>Lymphoma, B-Cell - enzymology</topic><topic>Lymphoma, Non-Hodgkin - blood</topic><topic>Lymphoma, Non-Hodgkin - enzymology</topic><topic>Male</topic><topic>Medical sciences</topic><topic>Middle Aged</topic><topic>mRNA</topic><topic>Neuron‐specific enolase</topic><topic>Phosphopyruvate hydratase</topic><topic>Phosphopyruvate Hydratase - blood</topic><topic>Pleural cavity</topic><topic>Post-transcription</topic><topic>Pyothorax‐associated lymphoma</topic><topic>Quantitative reverse transcription PCR</topic><topic>Reverse Transcriptase Polymerase Chain Reaction</topic><topic>RNA - metabolism</topic><topic>RNA, Messenger - metabolism</topic><topic>Serum levels</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Nakatsuka, Shin‐ichi</creatorcontrib><creatorcontrib>Nishiu, Mieko</creatorcontrib><creatorcontrib>Tomita, Yasuhiko</creatorcontrib><creatorcontrib>Miwa, Hideaki</creatorcontrib><creatorcontrib>Takakuwa, Tetsuya</creatorcontrib><creatorcontrib>Luchi, Keiji</creatorcontrib><creatorcontrib>Yamamoto, Satoru</creatorcontrib><creatorcontrib>Aozasa, Katsuyuki</creatorcontrib><collection>Pascal-Francis</collection><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>ProQuest SciTech Collection</collection><collection>ProQuest Natural Science Collection</collection><collection>ProQuest Central (Alumni Edition)</collection><collection>ProQuest Central UK/Ireland</collection><collection>ProQuest Central Essentials</collection><collection>Biological Science Collection</collection><collection>ProQuest Central</collection><collection>Natural Science Collection</collection><collection>ProQuest One Community College</collection><collection>ProQuest Central Korea</collection><collection>ProQuest Central Student</collection><collection>SciTech Premium Collection</collection><collection>ProQuest Biological Science Collection</collection><collection>Biological Science Database</collection><collection>Publicly Available Content Database</collection><collection>ProQuest One Academic Eastern Edition (DO NOT USE)</collection><collection>ProQuest One Academic</collection><collection>ProQuest One Academic UKI Edition</collection><collection>ProQuest Central China</collection><collection>MEDLINE - Academic</collection><collection>PubMed Central (Full Participant titles)</collection><jtitle>Cancer science</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Nakatsuka, Shin‐ichi</au><au>Nishiu, Mieko</au><au>Tomita, Yasuhiko</au><au>Miwa, Hideaki</au><au>Takakuwa, Tetsuya</au><au>Luchi, Keiji</au><au>Yamamoto, Satoru</au><au>Aozasa, Katsuyuki</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Enhanced Expression of Neuron‐specific Enolase (NSE) in Pyothorax‐associated Lymphoma (PAL)</atitle><jtitle>Cancer science</jtitle><addtitle>Jpn J Cancer Res</addtitle><date>2002-04</date><risdate>2002</risdate><volume>93</volume><issue>4</issue><spage>411</spage><epage>416</epage><pages>411-416</pages><issn>0910-5050</issn><issn>1347-9032</issn><eissn>1349-7006</eissn><eissn>1876-4673</eissn><coden>GANNA2</coden><abstract>Pyothorax‐associated lymphoma (PAL) is a B‐cell lymphoma of mostly large cell type developing in the pleural cavity of patients with long‐standing pyothorax. Neuron‐specific enolase (NSE) is an enolase comprising γ subunit and is located at high levels in neuronal and neuroendocrine cells, together with their neoplasias. Expression of NSE at protein and mRNA levels was examined in PAL and other types (non‐PAL) of non‐Hodgkin's lymphomas. In PAL, serum levels of NSE were elevated (5.32 to 168.0, mean 42.6 ng/ml) and tended to decrease after incisional biopsy followed by chemotherapy (2.38 to 195.5, mean 34.1 ng/ml). Two cell lines established from two cases of PAL produced and secreted NSE in the culture medium. Immunohistochemistry revealed that the positive rate for NSE staining in PAL (10 of 14 cases, 71.4%) was significantly higher than that in non‐PAL cases (6 of 38 cases, 15.8%) (P&lt;0.01). RT‐PCR analysis showed that the expression levels of NSE mRNA in two cell lines and a biopsy sample from PAL were rather similar to those of the control samples from non‐neoplastic lymph nodes. These findings suggest the posttranscriptional regulation of NSE in PAL. Thus, an elevation of serum NSE level in patients with chronic pyothorax may be an indicator of PAL development.</abstract><cop>Oxford, UK</cop><pub>Blackwell Publishing Ltd</pub><pmid>11985791</pmid><doi>10.1111/j.1349-7006.2002.tb01272.x</doi><tpages>6</tpages><oa>free_for_read</oa></addata></record>
fulltext fulltext
identifier ISSN: 0910-5050
ispartof Cancer science, 2002-04, Vol.93 (4), p.411-416
issn 0910-5050
1347-9032
1349-7006
1876-4673
language eng
recordid cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_5927012
source MEDLINE; IngentaConnect Free/Open Access Journals; EZB-FREE-00999 freely available EZB journals; Wiley Online Library All Journals; PubMed Central
subjects Adolescent
Adult
Aged
Biological and medical sciences
Biopsy
Cell culture
Cell Line, Tumor
Chemotherapy
Drug Therapy
Empyema, Pleural - metabolism
Female
Gene expression
Gene Expression Regulation, Enzymologic
Gene Expression Regulation, Neoplastic
Hematologic and hematopoietic diseases
Humans
Immunohistochemistry
Leukemias. Malignant lymphomas. Malignant reticulosis. Myelofibrosis
Lymph nodes
Lymphoma
Lymphoma - blood
Lymphoma - enzymology
Lymphoma, B-Cell - blood
Lymphoma, B-Cell - enzymology
Lymphoma, Non-Hodgkin - blood
Lymphoma, Non-Hodgkin - enzymology
Male
Medical sciences
Middle Aged
mRNA
Neuron‐specific enolase
Phosphopyruvate hydratase
Phosphopyruvate Hydratase - blood
Pleural cavity
Post-transcription
Pyothorax‐associated lymphoma
Quantitative reverse transcription PCR
Reverse Transcriptase Polymerase Chain Reaction
RNA - metabolism
RNA, Messenger - metabolism
Serum levels
title Enhanced Expression of Neuron‐specific Enolase (NSE) in Pyothorax‐associated Lymphoma (PAL)
url https://sfx.bib-bvb.de/sfx_tum?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&ctx_tim=2025-01-12T09%3A43%3A01IST&url_ver=Z39.88-2004&url_ctx_fmt=infofi/fmt:kev:mtx:ctx&rfr_id=info:sid/primo.exlibrisgroup.com:primo3-Article-proquest_pubme&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.atitle=Enhanced%20Expression%20of%20Neuron%E2%80%90specific%20Enolase%20(NSE)%20in%20Pyothorax%E2%80%90associated%20Lymphoma%20(PAL)&rft.jtitle=Cancer%20science&rft.au=Nakatsuka,%20Shin%E2%80%90ichi&rft.date=2002-04&rft.volume=93&rft.issue=4&rft.spage=411&rft.epage=416&rft.pages=411-416&rft.issn=0910-5050&rft.eissn=1349-7006&rft.coden=GANNA2&rft_id=info:doi/10.1111/j.1349-7006.2002.tb01272.x&rft_dat=%3Cproquest_pubme%3E71648341%3C/proquest_pubme%3E%3Curl%3E%3C/url%3E&disable_directlink=true&sfx.directlink=off&sfx.report_link=0&rft_id=info:oai/&rft_pqid=2400128525&rft_id=info:pmid/11985791&rfr_iscdi=true