Production of a Single‐chain Variable Fragment Antibody Recognizing Type III Mutant Epidermal Growth Factor Receptor

The type III deletion mutant of the epidermal growth factor receptor (EGFR) is a potential target in diagnostic and therapeutic approaches for those glioblastomas characterized by its expression. We previously raised a mouse monoclonal antibody, 3C10 (IgG2b) specifically recognizing this mutant EGFR...

Ausführliche Beschreibung

Gespeichert in:

Bibliographische Detailangaben
Veröffentlicht in:	Cancer science 2000-10, Vol.91 (10), p.1035-1043
Hauptverfasser:	Nakayashiki, Norihisa, Yoshikawa, Kazuhiro, Nakamura, Kazuyasu, Hanai, Nobuo, Okamoto, Kenta, Okamoto, Sho, Mizuno, Masaaki, Wakabayashi, Toshihiko, Saga, Sinsuke, Yoshida, Jun, Takahashi, Toshitada
Format:	Artikel
Sprache:	eng
Schlagworte:	3T3 Cells Amino Acid Sequence Animals Antibodies, Monoclonal - chemistry Antibodies, Monoclonal - genetics Antibodies, Monoclonal - immunology Antibody Formation Base Sequence Biological and medical sciences Cloning Cloning, Molecular Deletion mutant DNA Primers DNA, Complementary - analysis Epidermal growth factor Epidermal growth factor receptor Epidermal growth factor receptors Epitopes ErbB Receptors - genetics ErbB Receptors - immunology Gene Deletion Gene Expression Glioblastoma Immunofluorescence Immunoglobulin Fragments - chemistry Immunoglobulin Fragments - genetics Immunoglobulin Fragments - immunology Immunoglobulin G Inclusion bodies Medical sciences Mice Molecular Sequence Data Monoclonal antibodies Mutants Neurology Peptides Polymerase chain reaction Protein Folding Rapid Communication Recombinant Proteins - chemistry Recombinant Proteins - immunology RNA-directed DNA polymerase scFv Tumors of the nervous system. Phacomatoses Type III deletion mutant
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!

Schreiben Sie den ersten Kommentar!