Comprehensive genomic transcriptomic tumor-normal gene panel analysis for enhanced precision in patients with lung cancer

A CMS approved test for lung cancer is based on tumor-only analysis of a targeted 35 gene panel, specifically excluding the use of the patient's normal germline tissue. However, this tumor-only approach increases the risk of mistakenly identifying germline single nucleotide polymorphisms (SNPs)...

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Veröffentlicht in:	Oncotarget 2018-04, Vol.9 (27), p.19223-19232
Hauptverfasser:	Rabizadeh, Shahrooz, Garner, Chad, Sanborn, John Zachary, Benz, Stephen C, Reddy, Sandeep, Soon-Shiong, Patrick
Format:	Artikel
Sprache:	eng
Schlagworte:	Research Paper
Online-Zugang:	Volltext
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