Therapeutic role of meloxicam targeting secretory clusterin-mediated invasion in hepatocellular carcinoma cells

Recurrence and metastasis are the two leading causes of poor prognosis in patients with hepatocellular carcinoma (HCC). Secreted clusterin (sCLU) is a stress-induced chaperone that is overexpressed in HCC. However, the precise molecular mechanisms of sCLU in HCC invasion and migration are largely un...

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Veröffentlicht in:	Oncology letters 2018-05, Vol.15 (5), p.7191-7199
Hauptverfasser:	Zhong, Jingtao, Yu, Xiaoming, Dong, Xiaofeng, Lu, Hong, Zhou, Wuyuan, Li, Lei, Li, Zhongchao, Sun, Pengfei, Shi, Xuetao
Format:	Artikel
Sprache:	eng
Schlagworte:	Apoptosis Cancer therapies Chemotherapy Cytotoxicity Development and progression Drug therapy Genetic aspects Glycoproteins Health aspects Hepatitis Hepatocellular carcinoma Immunoglobulins Liver cancer Medical prognosis Meloxicam Metastasis Oncology Patient outcomes Proteins Studies
Online-Zugang:	Volltext
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