STAT3-enhancing germline mutations contribute to tumor-extrinsic immune evasion

Immune evasion and the suppression of antitumor responses during cancer progression are considered hallmarks of cancer and are typically attributed to tumor-derived factors. Although the molecular basis for the crosstalk between tumor and immune cells is an area of active investigation, whether host...

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Veröffentlicht in:The Journal of clinical investigation 2018-05, Vol.128 (5), p.1867-1872
Hauptverfasser: Kogan, Daniel, Grabner, Alexander, Yanucil, Christopher, Faul, Christian, Ulaganathan, Vijay Kumar
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Sprache:eng
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