Differential Changes in Expression of Gap Junction Proteins Connexin 26 and 32 during Hepatocarcinogenesis in Rats

We examined expressions of the gap junction proteins, connexin 26 (C×26) and 32 (C×32), in preneoplastic and neoplastic lesions during rat hepatocarcinogenesis. A marked reduction in the numher of C×32‐positive gap junctions was observed in 17% of the glutathione S‐transferase placental form‐positiv...

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Veröffentlicht in:	Cancer science 1992-11, Vol.83 (11), p.1210-1215
Hauptverfasser:	Sakamoto, Hirofumi, Oyamada, Masahito, Enomoto, Katsuhiko, Mori, Michio
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Biological and medical sciences Carcinogenesis Carcinogenesis, carcinogens and anticarcinogens Cell Membrane - enzymology Cell Membrane - physiology Chemical agents Connexin Connexin 26 Connexins Gap junction Gap junctions Glutathione Glutathione Transferase - analysis Hepatocarcinogenesis Hepatocellular carcinoma Hyperplasia Liver - pathology Liver - physiology Liver Neoplasms, Experimental - enzymology Liver Neoplasms, Experimental - etiology Liver Neoplasms, Experimental - physiopathology Male Medical sciences Membrane Proteins - physiology Nodules Placenta Precancerous Conditions - enzymology Precancerous Conditions - physiopathology Rabbits Rats Rats, Inbred F344 Tumors
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