Localization of Acidic and Basic Fibroblast Growth Factor mRNA in Human Brain Tumors

Acidic and basic fibroblast growth factors (aFGF and bFGF) are closely related peptide mitogens acting on both mesoderm‐ and neuroectoderm‐derived cells, including fibroblasts, endothelial cells and glial cells. In order to identify the expression of mRNAs for these growth factors, in situ hybridiza...

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Veröffentlicht in:	Cancer science 1991-09, Vol.82 (9), p.1022-1027
Hauptverfasser:	Akutsu, Yasuhiko, Aida, Takeo, Nakazawa, Shozo, Asano, Goro
Format:	Artikel
Sprache:	eng
Schlagworte:	Adolescent Adult Aged Astrocytoma Astrocytoma - chemistry Astrocytoma - genetics Autocrine signalling Base Sequence Biological and medical sciences brain Brain Neoplasms - chemistry Brain Neoplasms - genetics Brain tumors Carcinoma Cell proliferation DNA probes Endothelial cells Female Fibroblast growth factor fibroblast growth factor (acidic) Fibroblast growth factor 2 Fibroblast Growth Factors - analysis Fibroblast Growth Factors - genetics Fibroblasts Glial cells Glioma - chemistry Glioma - genetics Growth factors Humans Hybridization Hydrogen-Ion Concentration In situ hybridization – Human brain tumor Localization Male Medical sciences Meningioma - chemistry Meningioma - genetics Mesoderm Metastases Middle Aged Mitogens Molecular Sequence Data mRNA Neoplasia Neuroectoderm Neurology Neuronal-glial interactions Nucleic Acid Hybridization Paracrine signalling Pituitary Polymerase Chain Reaction RNA probes RNA, Messenger - analysis Tumor cells tumours
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