Reactive oxygen radicals and gaseous transmitters in carotid body activation by intermittent hypoxia

Sleep apnea is a prevalent respiratory disease characterized by periodic cessation of breathing during sleep causing intermittent hypoxia (IH). Sleep apnea patients and rodents exposed to IH exhibit elevated sympathetic nerve activity and hypertension. A heightened carotid body (CB) chemoreflex has...

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Veröffentlicht in:	Cell and tissue research 2018-05, Vol.372 (2), p.427-431
Hauptverfasser:	Prabhakar, Nanduri R., Peng, Ying-Jie, Yuan, Guoxiang, Nanduri, Jayasri
Format:	Artikel
Sprache:	eng
Schlagworte:	Active oxygen Animals Apnea Biomedical and Life Sciences Biomedicine Carbon monoxide Carotid body Carotid Body - metabolism Carotid Body - pathology Chemoreception (internal) Enzymes Gases - metabolism Gene regulation Heme Human Genetics Humans Hydrogen sulfide Hydrogen Sulfide - metabolism Hypertension Hypoxia Hypoxia - metabolism Hypoxia - pathology Hypoxia-inducible factor 1 Hypoxia-inducible factors Molecular Medicine Oxygenase Phosphorylation Proteomics Reactive oxygen species Reactive Oxygen Species - metabolism Respiratory diseases Review Sleep Sleep apnea Sleep disorders Telecommunications equipment Transcription
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