Cancer terminator viruses (CTV): A better solution for viral‐based therapy of cancer

In principle, viral gene therapy holds significant potential for the therapy of solid cancers. However, this promise has not been fully realized and systemic administration of viruses has not proven as successful as envisioned in the clinical arena. Our research is focused on developing the next gen...

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Veröffentlicht in:	Journal of cellular physiology 2018-08, Vol.233 (8), p.5684-5695
Hauptverfasser:	Emdad, Luni, Das, Swadesh K., Wang, Xiang‐Yang, Sarkar, Devanand, Fisher, Paul B.
Format:	Artikel
Sprache:	eng
Schlagworte:	Adenoviridae - genetics Angiogenesis Animal models Animals Apoptosis Apoptosis - genetics Cancer Cell death CTV Gene therapy Genetic Therapy - methods Humans Immune system Interleukins Lethality mda‐7/IL‐24 Melanoma Metastases Neoplasms - genetics Neoplasms - therapy Neoplasms - virology Neovascularization, Pathologic - genetics Neovascularization, Pathologic - virology Tropism Tumor cells Tumors Ultrasonic imaging Ultrasound viral therapy Virus Replication - genetics Viruses
Online-Zugang:	Volltext
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