The Origin of Chromosomal Replication Is Asymmetrically Positioned on the Mycobacterial Nucleoid, and the Timing of Its Firing Depends on HupB

The bacterial chromosome undergoes dynamic changes in response to ongoing cellular processes and adaptation to environmental conditions. Among the many proteins involved in maintaining this dynamism, the most abundant is the nucleoid-associated protein (NAP) HU. In mycobacteria, the HU homolog, HupB...

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Veröffentlicht in:	Journal of bacteriology 2018-05, Vol.200 (10)
Hauptverfasser:	Hołówka, Joanna, Trojanowski, Damian, Janczak, Mateusz, Jakimowicz, Dagmara, Zakrzewska-Czerwińska, Jolanta
Format:	Artikel
Sprache:	eng
Schlagworte:	Antibiotics Asymmetry Bacteria Bacterial Proteins - genetics Bacterial Proteins - metabolism Bacteriology Binding sites Cell cycle Cell Cycle - genetics Cell Division - genetics Chromosomes Chromosomes, Bacterial - genetics DNA Replication DNA, Bacterial - genetics DNA-Binding Proteins - genetics DNA-Binding Proteins - metabolism E coli Environmental conditions Escherichia coli - genetics Fluorescence Gene Expression Regulation, Bacterial Green fluorescent protein Green Fluorescent Proteins Histones Homology HupB protein Mycobacterium smegmatis - genetics Mycobacterium smegmatis - growth & development Origin Recognition Complex - genetics Origin Recognition Complex - metabolism Proteins Replication Replication initiation Replication origins Tuberculosis
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