Imaging αvβ3 integrin expression in skeletal metastases with 99mTc-maraciclatide single-photon emission computed tomography: detection and therapy response assessment

Purpose Osteoclast activity is an important factor in the pathogenesis of skeletal metastases and is a potential therapeutic target. This study aimed to determine if selective uptake of 99m Tc-maraciclatide, a radiopharmaceutical targeting α v β 3 integrin, occurs in prostate cancer (PCa) bone metas...

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