BRCA1/2 and TP53 mutation status associates with PD-1 and PD-L1 expression in ovarian cancer

Checkpoint molecules such as programmed cell death protein-1 (PD-1) and its ligand PD-L1 are critically required for tumor immune escape. The objective of this study was to investigate tumoral and mRNA-expression in a cohort of ovarian cancer (OC) patients in relation to tumor mutations. We analyzed...

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Veröffentlicht in:	Oncotarget 2018-04, Vol.9 (25), p.17501-17511
Hauptverfasser:	Wieser, Verena, Gaugg, Inge, Fleischer, Martina, Shivalingaiah, Giridhar, Wenzel, Soeren, Sprung, Susanne, Lax, Sigurd F, Zeimet, Alain G, Fiegl, Heidelinde, Marth, Christian
Format:	Artikel
Sprache:	eng
Schlagworte:	Research Paper
Online-Zugang:	Volltext
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