A nuclease specific to lepidopteran insects suppresses RNAi

More than 70% of all agricultural pests are insects in the order Lepidoptera, which, unlike other related insect orders, are not very sensitive to RNAi, limiting genetic studies of this insect group. However, the reason for this distinct lepidopteran characteristic is unknown. Previously, using tran...

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Veröffentlicht in:	The Journal of biological chemistry 2018-04, Vol.293 (16), p.6011-6021
Hauptverfasser:	Guan, Ruo-Bing, Li, Hai-Chao, Fan, Yu-Jie, Hu, Shao-Ru, Christiaens, Olivier, Smagghe, Guy, Miao, Xue-Xia
Format:	Artikel
Sprache:	eng
Schlagworte:	Amino Acid Sequence Animals Deoxyribonucleases - chemistry Deoxyribonucleases - genetics Deoxyribonucleases - metabolism dsRNA enzyme Gene Regulation Genes, Insect insect Insect Proteins - chemistry Insect Proteins - genetics Insect Proteins - metabolism Lepidoptera - chemistry Lepidoptera - genetics Lepidoptera - metabolism Lepidoptera-specific nuclease Models, Molecular Phylogeny REase Ribonucleases - chemistry Ribonucleases - genetics Ribonucleases - metabolism RNA Interference RNA Stability RNAi RNAi efficiency Sequence Alignment Transcriptome
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