Impact of Age-Related Mitochondrial Dysfunction and Exercise on Intestinal Microbiota Composition

Mitochondrial dysfunction is prevalent in the aging gastrointestinal tract. We investigated whether mitochondrial function in aging colonic crypts and exercise influences microbial gut communities in mice. Twelve PolgAmut/mut mice were randomly divided into a sedentary and exercise group at 4 months...

Ausführliche Beschreibung

Gespeichert in:

Bibliographische Detailangaben
Veröffentlicht in:	The journals of gerontology. Series A, Biological sciences and medical sciences Biological sciences and medical sciences, 2018-04, Vol.73 (5), p.571-578
Hauptverfasser:	Houghton, David, Stewart, Christopher J, Stamp, Craig, Nelson, Andrew, Aj Ami, Nadim J, Petrosino, Joseph F, Wipat, Anil, Trenell, Michael I, Turnbull, Douglass M, Greaves, Laura C
Format:	Artikel
Sprache:	eng
Schlagworte:	Age Aging Aging - physiology Animals Colon Exercise Feces - microbiology Gastrointestinal Microbiome Intestinal microflora Intestine Mice Microbiota Mitochondria Mitochondrial Diseases - physiopathology Physical Conditioning, Animal Random Allocation Ribonucleic acid RNA Sedentary Behavior The Journal of Gerontology: Biological Sciences
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!

Schreiben Sie den ersten Kommentar!