The long non-coding RNA uc.4 influences cell differentiation through the TGF-beta signaling pathway

In a previous study, we screened thousands of long non-coding RNAs (lncRNAs) to assess their potential relationship with congenital heart disease (CHD). In this study, uc.4 attracted our attention because of its high level of evolutionary conservation and its antisense orientation to the CASZ1 gene,...

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Veröffentlicht in:	Experimental & molecular medicine 2018-02, Vol.50 (2), p.e447-e447
Hauptverfasser:	Cheng, Zijie, Zhang, Qijun, Yin, Anwen, Feng, Mengwen, Li, Hua, Liu, Hailang, Li, Yun, Qian, Lingmei
Format:	Artikel
Sprache:	eng
Schlagworte:	13/1 13/2 13/31 38/1 38/39 38/44 38/61 38/77 631/136/142 631/136/2086/1456 82/80 Animals Antisense therapy Apoptosis Biomarkers Biomedical and Life Sciences Biomedicine Cell Cycle - genetics Cell Differentiation - genetics Cell Line Computational Biology - methods Coronary artery disease Danio rerio Databases, Genetic DNA-Binding Proteins - genetics DNA-Binding Proteins - metabolism Evolutionary conservation Gene Expression Gene Expression Profiling Genes, Lethal Heart Heart Defects, Congenital - genetics Heart Defects, Congenital - metabolism Heart diseases Humans Medical Biochemistry Mice Molecular Medicine Non-coding RNA Original original-article RNA, Long Noncoding - genetics Signal Transduction Stem Cells Transcription Factors - genetics Transcription Factors - metabolism Transforming Growth Factor beta - metabolism Transforming growth factor-b Zebrafish
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