NOTCH regulation of the endothelial cell phenotype

PURPOSE OF REVIEWThe formation of a hierarchical vascular network is a complex process that requires precise temporal and spatial integration of several signaling pathways. Amongst those, Notch has emerged as a key regulator of multiple steps that expand from endothelial sprouting to arterial specif...

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Veröffentlicht in:	Current opinion in hematology 2018-05, Vol.25 (3), p.212-218
Hauptverfasser:	Mack, Julia J, Iruela-Arispe, M Luisa
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Blood Flow Velocity - physiology Cell Proliferation - physiology Endothelial Cells - cytology Endothelial Cells - metabolism Humans Mechanotransduction, Cellular - physiology NADPH Oxidase 2 - metabolism Neovascularization, Physiologic - physiology Receptor, Notch1 - metabolism Receptors, CXCR4 - metabolism Shear Strength VASCULAR BIOLOGY: Edited by Edward F. Plow Vascular Endothelial Growth Factor A - metabolism
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