Parvalbumin interneuron mediated feedforward inhibition controls signal output in the deep layers of the perirhinal‐entorhinal cortex

The perirhinal (PER) and lateral entorhinal (LEC) cortex form an anatomical link between the neocortex and the hippocampus. However, neocortical activity is transmitted through the PER and LEC to the hippocampus with a low probability, suggesting the involvement of the inhibitory network. This study...

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Veröffentlicht in:	Hippocampus 2018-04, Vol.28 (4), p.281-296
Hauptverfasser:	Willems, Janske G. P., Wadman, Wytse J., Cappaert, Natalie L. M.
Format:	Artikel
Sprache:	eng
Schlagworte:	Action Potentials - physiology Animals Conductance Cortex (entorhinal) Cortex (insular) Electrical stimuli Entorhinal Cortex - cytology Entorhinal Cortex - physiology excitation/inhibition balance Feedback, Physiological - physiology Female Gating Hippocampus Interneurons Interneurons - cytology Interneurons - physiology Male Mice, Inbred C57BL Mice, Transgenic mouse Neural Inhibition - physiology parahippocampal region Parvalbumin Parvalbumins - metabolism patch clamp Patch-Clamp Techniques Perirhinal Cortex - cytology Perirhinal Cortex - physiology Pyramidal Cells - physiology pyramidal neurons Synapses - physiology Tissue Culture Techniques
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