One‐year weight losses in the Tianjin Gestational Diabetes Mellitus Prevention Programme: A randomized clinical trial
Aims To report the weight loss findings after the first year of a lifestyle intervention trial among women with gestational diabetes mellitus (GDM). Methods A total of 1180 women with GDM were randomly assigned (1:1) to receive a 4‐year lifestyle intervention (intervention group, n = 586) or standar...
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| Veröffentlicht in: | Diabetes, obesity & metabolism obesity & metabolism, 2018-05, Vol.20 (5), p.1246-1255 |
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| creator | Liu, Huikun Wang, Leishen Zhang, Shuang Leng, Junhong Li, Nan Li, Weiqin Wang, Jing Tian, Huiguang Qi, Lu Yang, Xilin Yu, Zhijie Tuomilehto, Jaakko Hu, Gang |
| description | Aims
To report the weight loss findings after the first year of a lifestyle intervention trial among women with gestational diabetes mellitus (GDM).
Methods
A total of 1180 women with GDM were randomly assigned (1:1) to receive a 4‐year lifestyle intervention (intervention group, n = 586) or standard care (control group, n = 594) between August 2009 and July 2011. Major elements of the intervention included 6 face‐to‐face sessions with study dieticians and two telephone calls in the first year, and two individual sessions and two telephone calls in each subsequent year.
Results
Among 79% of participants who completed the year 1 trial, mean weight loss was 0.82 kg (1.12% of initial weight) in the intervention group and 0.09 kg (0.03% of initial weight) in the control group (P = .001). In a prespecified subgroup analysis of people who completed the trial, weight loss was more pronounced in women who were overweight (body mass index ≥24 kg/m2) at baseline: mean weight loss 2.01 kg (2.87% of initial weight) in the intervention group and 0.44 kg (0.52% of initial weight) in the control group (P < .001). Compared with those in the control group, women in the intervention group had a greater decrease in waist circumference (1.76 cm vs 0.73 cm; P = .003) and body fat (0.50% vs 0.05% increase; P = .001).
Conclusion
The 1‐year lifestyle intervention led to significant weight losses after delivery in women who had GDM, and the effect was more pronounced in women who were overweight at baseline. |
| doi_str_mv | 10.1111/dom.13225 |
| format | Article |
| fullrecord | <record><control><sourceid>proquest_pubme</sourceid><recordid>TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_5899932</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><sourcerecordid>1990493313</sourcerecordid><originalsourceid>FETCH-LOGICAL-c4435-e58e5a0a8b4c995d53341e8d699e35a32b8de863b7d69704c151929e7ffa47953</originalsourceid><addsrcrecordid>eNp1kc1u1DAUhS0EoqWw4AWQJTawSOvfxGZRqWqhILUaFmVtOcmdGY8cu9hJR8Oqj9Bn5EnwdEoFSHjja9_PR8fnIvSakkNa1lEfh0PKGZNP0D4VNa_KoX56X7NKacL20IucV4QQwVXzHO0xzWvCeLOP1rMAP2_vNmATXoNbLEfsY86QsQt4XAK-cjasSn0OebSji8F6fOZsC2NhLsF7N04Zf01wA2HbLmVcJDsM8AGf4GRDMed-QI8774LryusxOetfomdz6zO8etgP0LdPH69OP1cXs_MvpycXVScElxVIBdISq1rRaS17ybmgoPpaa-DSctaqHlTN26ZcNUR0VFLNNDTzuRWNlvwAHe90r6d2gL4rJpP15jq5waaNidaZvzvBLc0i3hiptNacFYF3DwIpfp9KCGZwuSv_tgHilA3VmgjNOeUFffsPuopTKoFlwwiTRGlZb6n3O6pLJegE80czlJjtOE1JzNyPs7Bv_nT_SP6eXwGOdsDaedj8X8mczS53kr8AhfOr5w</addsrcrecordid><sourcetype>Open Access Repository</sourcetype><iscdi>true</iscdi><recordtype>article</recordtype><pqid>2025089563</pqid></control><display><type>article</type><title>One‐year weight losses in the Tianjin Gestational Diabetes Mellitus Prevention Programme: A randomized clinical trial</title><source>MEDLINE</source><source>Wiley Online Library Journals Frontfile Complete</source><creator>Liu, Huikun ; Wang, Leishen ; Zhang, Shuang ; Leng, Junhong ; Li, Nan ; Li, Weiqin ; Wang, Jing ; Tian, Huiguang ; Qi, Lu ; Yang, Xilin ; Yu, Zhijie ; Tuomilehto, Jaakko ; Hu, Gang</creator><creatorcontrib>Liu, Huikun ; Wang, Leishen ; Zhang, Shuang ; Leng, Junhong ; Li, Nan ; Li, Weiqin ; Wang, Jing ; Tian, Huiguang ; Qi, Lu ; Yang, Xilin ; Yu, Zhijie ; Tuomilehto, Jaakko ; Hu, Gang</creatorcontrib><description>Aims
To report the weight loss findings after the first year of a lifestyle intervention trial among women with gestational diabetes mellitus (GDM).
Methods
A total of 1180 women with GDM were randomly assigned (1:1) to receive a 4‐year lifestyle intervention (intervention group, n = 586) or standard care (control group, n = 594) between August 2009 and July 2011. Major elements of the intervention included 6 face‐to‐face sessions with study dieticians and two telephone calls in the first year, and two individual sessions and two telephone calls in each subsequent year.
Results
Among 79% of participants who completed the year 1 trial, mean weight loss was 0.82 kg (1.12% of initial weight) in the intervention group and 0.09 kg (0.03% of initial weight) in the control group (P = .001). In a prespecified subgroup analysis of people who completed the trial, weight loss was more pronounced in women who were overweight (body mass index ≥24 kg/m2) at baseline: mean weight loss 2.01 kg (2.87% of initial weight) in the intervention group and 0.44 kg (0.52% of initial weight) in the control group (P < .001). Compared with those in the control group, women in the intervention group had a greater decrease in waist circumference (1.76 cm vs 0.73 cm; P = .003) and body fat (0.50% vs 0.05% increase; P = .001).
Conclusion
The 1‐year lifestyle intervention led to significant weight losses after delivery in women who had GDM, and the effect was more pronounced in women who were overweight at baseline.</description><identifier>ISSN: 1462-8902</identifier><identifier>EISSN: 1463-1326</identifier><identifier>DOI: 10.1111/dom.13225</identifier><identifier>PMID: 29360237</identifier><language>eng</language><publisher>Oxford, UK: Blackwell Publishing Ltd</publisher><subject>Adult ; Body fat ; Body Mass Index ; Body weight ; Body weight loss ; China - epidemiology ; Clinical trials ; Diabetes ; Diabetes mellitus ; Diabetes Mellitus, Type 2 - epidemiology ; Diabetes Mellitus, Type 2 - etiology ; Diabetes Mellitus, Type 2 - prevention & control ; Diabetes, Gestational - physiopathology ; Evidence-based medicine ; Female ; Follow-Up Studies ; Gestational diabetes ; Health risk assessment ; Healthy Lifestyle ; Humans ; Intention to Treat Analysis ; Lifestyles ; Obesity - physiopathology ; Obesity - therapy ; Overweight ; Overweight - physiopathology ; Overweight - therapy ; Patient Dropouts ; Patient Education as Topic ; Postpartum Period ; Pregnancy ; randomized clinical trials ; Risk ; Time Factors ; Weight Loss ; Weight Reduction Programs ; Young Adult</subject><ispartof>Diabetes, obesity & metabolism, 2018-05, Vol.20 (5), p.1246-1255</ispartof><rights>2018 John Wiley & Sons Ltd</rights><rights>2018 John Wiley & Sons Ltd.</rights><lds50>peer_reviewed</lds50><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c4435-e58e5a0a8b4c995d53341e8d699e35a32b8de863b7d69704c151929e7ffa47953</citedby><cites>FETCH-LOGICAL-c4435-e58e5a0a8b4c995d53341e8d699e35a32b8de863b7d69704c151929e7ffa47953</cites><orcidid>0000-0002-6172-8017</orcidid></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://onlinelibrary.wiley.com/doi/pdf/10.1111%2Fdom.13225$$EPDF$$P50$$Gwiley$$H</linktopdf><linktohtml>$$Uhttps://onlinelibrary.wiley.com/doi/full/10.1111%2Fdom.13225$$EHTML$$P50$$Gwiley$$H</linktohtml><link.rule.ids>230,314,776,780,881,1411,27901,27902,45550,45551</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/29360237$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Liu, Huikun</creatorcontrib><creatorcontrib>Wang, Leishen</creatorcontrib><creatorcontrib>Zhang, Shuang</creatorcontrib><creatorcontrib>Leng, Junhong</creatorcontrib><creatorcontrib>Li, Nan</creatorcontrib><creatorcontrib>Li, Weiqin</creatorcontrib><creatorcontrib>Wang, Jing</creatorcontrib><creatorcontrib>Tian, Huiguang</creatorcontrib><creatorcontrib>Qi, Lu</creatorcontrib><creatorcontrib>Yang, Xilin</creatorcontrib><creatorcontrib>Yu, Zhijie</creatorcontrib><creatorcontrib>Tuomilehto, Jaakko</creatorcontrib><creatorcontrib>Hu, Gang</creatorcontrib><title>One‐year weight losses in the Tianjin Gestational Diabetes Mellitus Prevention Programme: A randomized clinical trial</title><title>Diabetes, obesity & metabolism</title><addtitle>Diabetes Obes Metab</addtitle><description>Aims
To report the weight loss findings after the first year of a lifestyle intervention trial among women with gestational diabetes mellitus (GDM).
Methods
A total of 1180 women with GDM were randomly assigned (1:1) to receive a 4‐year lifestyle intervention (intervention group, n = 586) or standard care (control group, n = 594) between August 2009 and July 2011. Major elements of the intervention included 6 face‐to‐face sessions with study dieticians and two telephone calls in the first year, and two individual sessions and two telephone calls in each subsequent year.
Results
Among 79% of participants who completed the year 1 trial, mean weight loss was 0.82 kg (1.12% of initial weight) in the intervention group and 0.09 kg (0.03% of initial weight) in the control group (P = .001). In a prespecified subgroup analysis of people who completed the trial, weight loss was more pronounced in women who were overweight (body mass index ≥24 kg/m2) at baseline: mean weight loss 2.01 kg (2.87% of initial weight) in the intervention group and 0.44 kg (0.52% of initial weight) in the control group (P < .001). Compared with those in the control group, women in the intervention group had a greater decrease in waist circumference (1.76 cm vs 0.73 cm; P = .003) and body fat (0.50% vs 0.05% increase; P = .001).
Conclusion
The 1‐year lifestyle intervention led to significant weight losses after delivery in women who had GDM, and the effect was more pronounced in women who were overweight at baseline.</description><subject>Adult</subject><subject>Body fat</subject><subject>Body Mass Index</subject><subject>Body weight</subject><subject>Body weight loss</subject><subject>China - epidemiology</subject><subject>Clinical trials</subject><subject>Diabetes</subject><subject>Diabetes mellitus</subject><subject>Diabetes Mellitus, Type 2 - epidemiology</subject><subject>Diabetes Mellitus, Type 2 - etiology</subject><subject>Diabetes Mellitus, Type 2 - prevention & control</subject><subject>Diabetes, Gestational - physiopathology</subject><subject>Evidence-based medicine</subject><subject>Female</subject><subject>Follow-Up Studies</subject><subject>Gestational diabetes</subject><subject>Health risk assessment</subject><subject>Healthy Lifestyle</subject><subject>Humans</subject><subject>Intention to Treat Analysis</subject><subject>Lifestyles</subject><subject>Obesity - physiopathology</subject><subject>Obesity - therapy</subject><subject>Overweight</subject><subject>Overweight - physiopathology</subject><subject>Overweight - therapy</subject><subject>Patient Dropouts</subject><subject>Patient Education as Topic</subject><subject>Postpartum Period</subject><subject>Pregnancy</subject><subject>randomized clinical trials</subject><subject>Risk</subject><subject>Time Factors</subject><subject>Weight Loss</subject><subject>Weight Reduction Programs</subject><subject>Young Adult</subject><issn>1462-8902</issn><issn>1463-1326</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2018</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNp1kc1u1DAUhS0EoqWw4AWQJTawSOvfxGZRqWqhILUaFmVtOcmdGY8cu9hJR8Oqj9Bn5EnwdEoFSHjja9_PR8fnIvSakkNa1lEfh0PKGZNP0D4VNa_KoX56X7NKacL20IucV4QQwVXzHO0xzWvCeLOP1rMAP2_vNmATXoNbLEfsY86QsQt4XAK-cjasSn0OebSji8F6fOZsC2NhLsF7N04Zf01wA2HbLmVcJDsM8AGf4GRDMed-QI8774LryusxOetfomdz6zO8etgP0LdPH69OP1cXs_MvpycXVScElxVIBdISq1rRaS17ybmgoPpaa-DSctaqHlTN26ZcNUR0VFLNNDTzuRWNlvwAHe90r6d2gL4rJpP15jq5waaNidaZvzvBLc0i3hiptNacFYF3DwIpfp9KCGZwuSv_tgHilA3VmgjNOeUFffsPuopTKoFlwwiTRGlZb6n3O6pLJegE80czlJjtOE1JzNyPs7Bv_nT_SP6eXwGOdsDaedj8X8mczS53kr8AhfOr5w</recordid><startdate>201805</startdate><enddate>201805</enddate><creator>Liu, Huikun</creator><creator>Wang, Leishen</creator><creator>Zhang, Shuang</creator><creator>Leng, Junhong</creator><creator>Li, Nan</creator><creator>Li, Weiqin</creator><creator>Wang, Jing</creator><creator>Tian, Huiguang</creator><creator>Qi, Lu</creator><creator>Yang, Xilin</creator><creator>Yu, Zhijie</creator><creator>Tuomilehto, Jaakko</creator><creator>Hu, Gang</creator><general>Blackwell Publishing Ltd</general><general>Wiley Subscription Services, Inc</general><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7T5</scope><scope>7TK</scope><scope>H94</scope><scope>K9.</scope><scope>7X8</scope><scope>5PM</scope><orcidid>https://orcid.org/0000-0002-6172-8017</orcidid></search><sort><creationdate>201805</creationdate><title>One‐year weight losses in the Tianjin Gestational Diabetes Mellitus Prevention Programme: A randomized clinical trial</title><author>Liu, Huikun ; Wang, Leishen ; Zhang, Shuang ; Leng, Junhong ; Li, Nan ; Li, Weiqin ; Wang, Jing ; Tian, Huiguang ; Qi, Lu ; Yang, Xilin ; Yu, Zhijie ; Tuomilehto, Jaakko ; Hu, Gang</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c4435-e58e5a0a8b4c995d53341e8d699e35a32b8de863b7d69704c151929e7ffa47953</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2018</creationdate><topic>Adult</topic><topic>Body fat</topic><topic>Body Mass Index</topic><topic>Body weight</topic><topic>Body weight loss</topic><topic>China - epidemiology</topic><topic>Clinical trials</topic><topic>Diabetes</topic><topic>Diabetes mellitus</topic><topic>Diabetes Mellitus, Type 2 - epidemiology</topic><topic>Diabetes Mellitus, Type 2 - etiology</topic><topic>Diabetes Mellitus, Type 2 - prevention & control</topic><topic>Diabetes, Gestational - physiopathology</topic><topic>Evidence-based medicine</topic><topic>Female</topic><topic>Follow-Up Studies</topic><topic>Gestational diabetes</topic><topic>Health risk assessment</topic><topic>Healthy Lifestyle</topic><topic>Humans</topic><topic>Intention to Treat Analysis</topic><topic>Lifestyles</topic><topic>Obesity - physiopathology</topic><topic>Obesity - therapy</topic><topic>Overweight</topic><topic>Overweight - physiopathology</topic><topic>Overweight - therapy</topic><topic>Patient Dropouts</topic><topic>Patient Education as Topic</topic><topic>Postpartum Period</topic><topic>Pregnancy</topic><topic>randomized clinical trials</topic><topic>Risk</topic><topic>Time Factors</topic><topic>Weight Loss</topic><topic>Weight Reduction Programs</topic><topic>Young Adult</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Liu, Huikun</creatorcontrib><creatorcontrib>Wang, Leishen</creatorcontrib><creatorcontrib>Zhang, Shuang</creatorcontrib><creatorcontrib>Leng, Junhong</creatorcontrib><creatorcontrib>Li, Nan</creatorcontrib><creatorcontrib>Li, Weiqin</creatorcontrib><creatorcontrib>Wang, Jing</creatorcontrib><creatorcontrib>Tian, Huiguang</creatorcontrib><creatorcontrib>Qi, Lu</creatorcontrib><creatorcontrib>Yang, Xilin</creatorcontrib><creatorcontrib>Yu, Zhijie</creatorcontrib><creatorcontrib>Tuomilehto, Jaakko</creatorcontrib><creatorcontrib>Hu, Gang</creatorcontrib><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>Immunology Abstracts</collection><collection>Neurosciences Abstracts</collection><collection>AIDS and Cancer Research Abstracts</collection><collection>ProQuest Health & Medical Complete (Alumni)</collection><collection>MEDLINE - Academic</collection><collection>PubMed Central (Full Participant titles)</collection><jtitle>Diabetes, obesity & metabolism</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Liu, Huikun</au><au>Wang, Leishen</au><au>Zhang, Shuang</au><au>Leng, Junhong</au><au>Li, Nan</au><au>Li, Weiqin</au><au>Wang, Jing</au><au>Tian, Huiguang</au><au>Qi, Lu</au><au>Yang, Xilin</au><au>Yu, Zhijie</au><au>Tuomilehto, Jaakko</au><au>Hu, Gang</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>One‐year weight losses in the Tianjin Gestational Diabetes Mellitus Prevention Programme: A randomized clinical trial</atitle><jtitle>Diabetes, obesity & metabolism</jtitle><addtitle>Diabetes Obes Metab</addtitle><date>2018-05</date><risdate>2018</risdate><volume>20</volume><issue>5</issue><spage>1246</spage><epage>1255</epage><pages>1246-1255</pages><issn>1462-8902</issn><eissn>1463-1326</eissn><abstract>Aims
To report the weight loss findings after the first year of a lifestyle intervention trial among women with gestational diabetes mellitus (GDM).
Methods
A total of 1180 women with GDM were randomly assigned (1:1) to receive a 4‐year lifestyle intervention (intervention group, n = 586) or standard care (control group, n = 594) between August 2009 and July 2011. Major elements of the intervention included 6 face‐to‐face sessions with study dieticians and two telephone calls in the first year, and two individual sessions and two telephone calls in each subsequent year.
Results
Among 79% of participants who completed the year 1 trial, mean weight loss was 0.82 kg (1.12% of initial weight) in the intervention group and 0.09 kg (0.03% of initial weight) in the control group (P = .001). In a prespecified subgroup analysis of people who completed the trial, weight loss was more pronounced in women who were overweight (body mass index ≥24 kg/m2) at baseline: mean weight loss 2.01 kg (2.87% of initial weight) in the intervention group and 0.44 kg (0.52% of initial weight) in the control group (P < .001). Compared with those in the control group, women in the intervention group had a greater decrease in waist circumference (1.76 cm vs 0.73 cm; P = .003) and body fat (0.50% vs 0.05% increase; P = .001).
Conclusion
The 1‐year lifestyle intervention led to significant weight losses after delivery in women who had GDM, and the effect was more pronounced in women who were overweight at baseline.</abstract><cop>Oxford, UK</cop><pub>Blackwell Publishing Ltd</pub><pmid>29360237</pmid><doi>10.1111/dom.13225</doi><tpages>10</tpages><orcidid>https://orcid.org/0000-0002-6172-8017</orcidid><oa>free_for_read</oa></addata></record> |
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| source | MEDLINE; Wiley Online Library Journals Frontfile Complete |
| subjects | Adult Body fat Body Mass Index Body weight Body weight loss China - epidemiology Clinical trials Diabetes Diabetes mellitus Diabetes Mellitus, Type 2 - epidemiology Diabetes Mellitus, Type 2 - etiology Diabetes Mellitus, Type 2 - prevention & control Diabetes, Gestational - physiopathology Evidence-based medicine Female Follow-Up Studies Gestational diabetes Health risk assessment Healthy Lifestyle Humans Intention to Treat Analysis Lifestyles Obesity - physiopathology Obesity - therapy Overweight Overweight - physiopathology Overweight - therapy Patient Dropouts Patient Education as Topic Postpartum Period Pregnancy randomized clinical trials Risk Time Factors Weight Loss Weight Reduction Programs Young Adult |
| title | One‐year weight losses in the Tianjin Gestational Diabetes Mellitus Prevention Programme: A randomized clinical trial |
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