Multicomponent polysaccharide–protein bioconjugation in the development of antibacterial glycoconjugate vaccine candidates† †Electronic supplementary information (ESI) available. See DOI: 10.1039/c7sc05467j

A multicomponent reaction enables the one-pot assembly of immunogenic multivalent glycoconjugates. A new synthetic strategy for the development of multivalent antibacterial glycoconjugate vaccines is described. The approach comprises the utilization of an isocyanide-based multicomponent process for...

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Veröffentlicht in:	Chemical science (Cambridge) 2018-01, Vol.9 (9), p.2581-2588
Hauptverfasser:	Méndez, Yanira, Chang, Janoi, Humpierre, Ana R., Zanuy, Abel, Garrido, Raine, Vasco, Aldrin V., Pedroso, Jessy, Santana, Darielys, Rodríguez, Laura M., García-Rivera, Dagmar, Valdés, Yury, Vérez-Bencomo, Vicente, Rivera, Daniel G.
Format:	Artikel
Sprache:	eng
Schlagworte:	Chemistry
Online-Zugang:	Volltext
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