Next-generation sequencing provides an added value in determining drug resistance and viral tropism in Cameroonian HIV-1 vertically infected children

With limited and low-genetic barrier drugs used for the prevention of mother-to-child transmission (PMTCT) of HIV in sub-Saharan Africa, vertically transmitted HIV-1 drug-resistance (HIVDR) is concerning and might prompt optimal pediatric strategies.The aim of this study was to ascertain HIVDR and v...

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Veröffentlicht in:	Medicine (Baltimore) 2018-03, Vol.97 (13), p.e0176-e0176
Hauptverfasser:	Fokam, Joseph, Bellocchi, Maria C., Armenia, Daniele, Nanfack, Aubin J., Carioti, Luca, Continenza, Fabio, Takou, Desire, Temgoua, Edith S., Tangimpundu, Charlotte, Torimiro, Judith N., Koki, Paul N., Fokunang, Charles N., Cappelli, Giulia, Ndjolo, Alexis, Colizzi, Vittorio, Ceccherini-Silberstein, Francesca, Perno, Carlo-Federico, Santoro, Maria M.
Format:	Artikel
Sprache:	eng
Schlagworte:	Anti-HIV Agents - administration & dosage Anti-HIV Agents - therapeutic use Cameroon CD4 Lymphocyte Count Child Child, Preschool Drug Resistance, Viral - genetics Female High-Throughput Nucleotide Sequencing HIV Infections - transmission HIV Infections - virology HIV-1 - genetics Humans Infectious Disease Transmission, Vertical - prevention & control Male Observational Study RNA, Viral Viral Tropism - genetics
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