Quantitative high‐throughput screening identifies cytoprotective molecules that enhance SUMO conjugation via the inhibition of SUMO‐specific protease (SENP)2

The development of novel neuroprotective treatments for acute stroke has been fraught with failures, which supports the view of ischemic brain damage as a highly complex multifactorial process. Post‐translational modifications such as small ubiquitin‐like modifier (SUMO)ylation have emerged as criti...

Ausführliche Beschreibung