Cyanobacteria: Promising biocatalysts for sustainable chemical production
Cyanobacteria are photosynthetic prokaryotes showing great promise as biocatalysts for the direct conversion of CO2 into fuels, chemicals, and other value-added products. Introduction of just a few heterologous genes can endow cyanobacteria with the ability to transform specific central metabolites...
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| Veröffentlicht in: | The Journal of biological chemistry 2018-04, Vol.293 (14), p.5044-5052 |
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| container_issue | 14 |
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| container_title | The Journal of biological chemistry |
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| creator | Knoot, Cory J. Ungerer, Justin Wangikar, Pramod P. Pakrasi, Himadri B. |
| description | Cyanobacteria are photosynthetic prokaryotes showing great promise as biocatalysts for the direct conversion of CO2 into fuels, chemicals, and other value-added products. Introduction of just a few heterologous genes can endow cyanobacteria with the ability to transform specific central metabolites into many end products. Recent engineering efforts have centered around harnessing the potential of these microbial biofactories for sustainable production of chemicals conventionally produced from fossil fuels. Here, we present an overview of the unique chemistry that cyanobacteria have been co-opted to perform. We highlight key lessons learned from these engineering efforts and discuss advantages and disadvantages of various approaches. |
| doi_str_mv | 10.1074/jbc.R117.815886 |
| format | Article |
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| source | MEDLINE; EZB-FREE-00999 freely available EZB journals; PubMed Central; Alma/SFX Local Collection |
| subjects | Biocatalysis biofuel Biofuels - microbiology Biological Products - metabolism cyanobacteria Cyanobacteria - chemistry Cyanobacteria - genetics Cyanobacteria - physiology Industrial Microbiology - methods metabolic engineering Metabolic Engineering - methods Metabolic Flux Analysis - methods natural product Photosynthesis Thematic Minireviews |
| title | Cyanobacteria: Promising biocatalysts for sustainable chemical production |
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