Single blood transfusion induces the production of donor-specific alloantibodies and regulatory T cells mainly in the spleen

A single donor-specific transfusion induces alloantibodies and Treg cells Abstract Donor-specific blood transfusion is known to induce alloresponses and lead to immunosuppression. We examined their underlying mechanisms by employing fully allogeneic rat combinations. Transfused recipients efficientl...

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Veröffentlicht in:	International immunology 2018-03, Vol.30 (2), p.53-67
Hauptverfasser:	Ueta, Hisashi, Kitazawa, Yusuke, Sawanobori, Yasushi, Ueno, Takamasa, Ueha, Satoshi, Matsushima, Kouji, Matsuno, Kenjiro
Format:	Artikel
Sprache:	eng
Schlagworte:	Original Research Papers
Online-Zugang:	Volltext
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