Illumina short-read and MinION long-read WGS to characterize the molecular epidemiology of an NDM-1 Serratia marcescens outbreak in Romania

Serratia marcescens is an emerging nosocomial pathogen, and the carbapenemase blaNDM has been reported in several surveys in Romania. We aimed to investigate the molecular epidemiology of S. marcescens in two Romanian hospitals over 2010-15, including a neonatal NDM-1 S. marcescens outbreak. Isolate...

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Veröffentlicht in:	Journal of antimicrobial chemotherapy 2018-03, Vol.73 (3), p.672-679
Hauptverfasser:	Phan, H T T, Stoesser, N, Maciuca, I E, Toma, F, Szekely, E, Flonta, M, Hubbard, A T M, Pankhurst, L, Do, T, Peto, T E A, Walker, A S, Crook, D W, Timofte, D
Format:	Artikel
Sprache:	eng
Schlagworte:	beta-Lactamases - biosynthesis beta-Lactamases - genetics Disease Outbreaks DNA, Bacterial - genetics Enterobacteriaceae - genetics Enterobacteriaceae Infections - epidemiology Feces - microbiology Gene Transfer, Horizontal Genome, Bacterial Hospitals Humans Klebsiella Infections - epidemiology Klebsiella pneumoniae - genetics Original Research Plasmids - genetics Romania - epidemiology Sequence Analysis, DNA Serratia Infections - epidemiology Serratia marcescens - enzymology Serratia marcescens - genetics Whole Genome Sequencing - methods
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