Frontline brentuximab vedotin in breast implant‐associated anaplastic large‐cell lymphoma
Key Clinical Message We report a woman who developed BIA‐ALCL 9 years after saline implant placement. The lymphoma manifested as a mass lesion associated with axillary lymphadenopathy. She was successfully treated with brentuximab vedotin with minimal toxicity. Brentuximab vedotin may be a promising...
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Veröffentlicht in: | Clinical case reports 2018-04, Vol.6 (4), p.634-637 |
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creator | Alderuccio, Juan Pablo Desai, Amrita Yepes, Monica M. Chapman, Jennifer R. Vega, Francisco Lossos, Izidore S. |
description | Key Clinical Message
We report a woman who developed BIA‐ALCL 9 years after saline implant placement. The lymphoma manifested as a mass lesion associated with axillary lymphadenopathy. She was successfully treated with brentuximab vedotin with minimal toxicity. Brentuximab vedotin may be a promising frontline therapeutic modality for patients with BIA‐ALCL.
Breast implant‐associated anaplastic large cell lymphoma (BIA‐ALCL) is a rare peripheral T‐cell lymphoma. BIA‐ALCL presenting with a capsular mass show shorter survival despite implant removal followed by CHOP‐like chemotherapy. We present a patient with BIA‐ALCL successfully treated with frontline brentuximab vedotin. |
doi_str_mv | 10.1002/ccr3.1382 |
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We report a woman who developed BIA‐ALCL 9 years after saline implant placement. The lymphoma manifested as a mass lesion associated with axillary lymphadenopathy. She was successfully treated with brentuximab vedotin with minimal toxicity. Brentuximab vedotin may be a promising frontline therapeutic modality for patients with BIA‐ALCL.
Breast implant‐associated anaplastic large cell lymphoma (BIA‐ALCL) is a rare peripheral T‐cell lymphoma. BIA‐ALCL presenting with a capsular mass show shorter survival despite implant removal followed by CHOP‐like chemotherapy. We present a patient with BIA‐ALCL successfully treated with frontline brentuximab vedotin.</description><identifier>ISSN: 2050-0904</identifier><identifier>EISSN: 2050-0904</identifier><identifier>DOI: 10.1002/ccr3.1382</identifier><identifier>PMID: 29636930</identifier><language>eng</language><publisher>England: John Wiley & Sons, Inc</publisher><subject>Breast implant‐associated anaplastic large‐cell lymphoma and brentuximab vedotin ; Case Report ; Case Reports ; Immunotherapy ; Monoclonal antibodies ; non‐Hodgkin's lymphoma ; Targeted cancer therapy</subject><ispartof>Clinical case reports, 2018-04, Vol.6 (4), p.634-637</ispartof><rights>2018 The Authors. published by John Wiley & Sons Ltd.</rights><rights>2018. This work is published under http://creativecommons.org/licenses/by/4.0/ (the “License”). Notwithstanding the ProQuest Terms and Conditions, you may use this content in accordance with the terms of the License.</rights><lds50>peer_reviewed</lds50><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c3402-69cff60879d39714262371abf4760c9da01798e21167ee9430d9f95644ae8fe13</citedby><cites>FETCH-LOGICAL-c3402-69cff60879d39714262371abf4760c9da01798e21167ee9430d9f95644ae8fe13</cites><orcidid>0000-0002-2690-3377</orcidid></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://www.ncbi.nlm.nih.gov/pmc/articles/PMC5889253/pdf/$$EPDF$$P50$$Gpubmedcentral$$Hfree_for_read</linktopdf><linktohtml>$$Uhttps://www.ncbi.nlm.nih.gov/pmc/articles/PMC5889253/$$EHTML$$P50$$Gpubmedcentral$$Hfree_for_read</linktohtml><link.rule.ids>230,314,724,777,781,861,882,1412,11543,27905,27906,45555,45556,46033,46457,53772,53774</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/29636930$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Alderuccio, Juan Pablo</creatorcontrib><creatorcontrib>Desai, Amrita</creatorcontrib><creatorcontrib>Yepes, Monica M.</creatorcontrib><creatorcontrib>Chapman, Jennifer R.</creatorcontrib><creatorcontrib>Vega, Francisco</creatorcontrib><creatorcontrib>Lossos, Izidore S.</creatorcontrib><title>Frontline brentuximab vedotin in breast implant‐associated anaplastic large‐cell lymphoma</title><title>Clinical case reports</title><addtitle>Clin Case Rep</addtitle><description>Key Clinical Message
We report a woman who developed BIA‐ALCL 9 years after saline implant placement. The lymphoma manifested as a mass lesion associated with axillary lymphadenopathy. She was successfully treated with brentuximab vedotin with minimal toxicity. Brentuximab vedotin may be a promising frontline therapeutic modality for patients with BIA‐ALCL.
Breast implant‐associated anaplastic large cell lymphoma (BIA‐ALCL) is a rare peripheral T‐cell lymphoma. BIA‐ALCL presenting with a capsular mass show shorter survival despite implant removal followed by CHOP‐like chemotherapy. We present a patient with BIA‐ALCL successfully treated with frontline brentuximab vedotin.</description><subject>Breast implant‐associated anaplastic large‐cell lymphoma and brentuximab vedotin</subject><subject>Case Report</subject><subject>Case Reports</subject><subject>Immunotherapy</subject><subject>Monoclonal antibodies</subject><subject>non‐Hodgkin's lymphoma</subject><subject>Targeted cancer therapy</subject><issn>2050-0904</issn><issn>2050-0904</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2018</creationdate><recordtype>article</recordtype><sourceid>24P</sourceid><sourceid>WIN</sourceid><sourceid>ABUWG</sourceid><sourceid>AFKRA</sourceid><sourceid>AZQEC</sourceid><sourceid>BENPR</sourceid><sourceid>CCPQU</sourceid><sourceid>DWQXO</sourceid><recordid>eNp1kc9KxDAQxoMoKqsHX0AKnjx0d5K0aXMRZPEfLAiiRwlpmmokbdakq-7NR_AZfRKz7irrQRjIMPPjm5l8CB1gGGIAMlLK0yGmJdlAuwRySIFDtrmW76D9EJ4AAENBcgzbaIdwRhmnsIvuz73rems6nVRed_3szbSySl507XrTJTFiWYY-Me3Uyq7_fP-QIThlZK_rRHYyVkNvVGKlf9Cxq7S1iZ2300fXyj201Ugb9P7qHaC787Pb8WU6ub64Gp9OUkUzICnjqmkYlAWvKS9wRhihBZZVkxUMFK8l4IKXmmDMCq15RqHmDc9ZlkldNhrTATpZ6k5nVatrFQ_x0oqpj8f4uXDSiL-dzjyKB_ci8rLkJKdR4Ggl4N3zTIdePLmZ7-LOggAhFHOG80gdLynlXQheN78TMIiFGWJhhliYEdnD9ZV-yZ-vj8BoCbwaq-f_K4nx-IZ-S34Be2qWig</recordid><startdate>201804</startdate><enddate>201804</enddate><creator>Alderuccio, Juan Pablo</creator><creator>Desai, Amrita</creator><creator>Yepes, Monica M.</creator><creator>Chapman, Jennifer R.</creator><creator>Vega, Francisco</creator><creator>Lossos, Izidore S.</creator><general>John Wiley & Sons, Inc</general><general>John Wiley and Sons Inc</general><scope>24P</scope><scope>WIN</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>3V.</scope><scope>7X7</scope><scope>7XB</scope><scope>8FI</scope><scope>8FJ</scope><scope>8FK</scope><scope>ABUWG</scope><scope>AFKRA</scope><scope>AZQEC</scope><scope>BENPR</scope><scope>CCPQU</scope><scope>DWQXO</scope><scope>FYUFA</scope><scope>GHDGH</scope><scope>K9.</scope><scope>M0S</scope><scope>PIMPY</scope><scope>PQEST</scope><scope>PQQKQ</scope><scope>PQUKI</scope><scope>PRINS</scope><scope>5PM</scope><orcidid>https://orcid.org/0000-0002-2690-3377</orcidid></search><sort><creationdate>201804</creationdate><title>Frontline brentuximab vedotin in breast implant‐associated anaplastic large‐cell lymphoma</title><author>Alderuccio, Juan Pablo ; 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We report a woman who developed BIA‐ALCL 9 years after saline implant placement. The lymphoma manifested as a mass lesion associated with axillary lymphadenopathy. She was successfully treated with brentuximab vedotin with minimal toxicity. Brentuximab vedotin may be a promising frontline therapeutic modality for patients with BIA‐ALCL.
Breast implant‐associated anaplastic large cell lymphoma (BIA‐ALCL) is a rare peripheral T‐cell lymphoma. BIA‐ALCL presenting with a capsular mass show shorter survival despite implant removal followed by CHOP‐like chemotherapy. We present a patient with BIA‐ALCL successfully treated with frontline brentuximab vedotin.</abstract><cop>England</cop><pub>John Wiley & Sons, Inc</pub><pmid>29636930</pmid><doi>10.1002/ccr3.1382</doi><tpages>4</tpages><orcidid>https://orcid.org/0000-0002-2690-3377</orcidid><oa>free_for_read</oa></addata></record> |
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subjects | Breast implant‐associated anaplastic large‐cell lymphoma and brentuximab vedotin Case Report Case Reports Immunotherapy Monoclonal antibodies non‐Hodgkin's lymphoma Targeted cancer therapy |
title | Frontline brentuximab vedotin in breast implant‐associated anaplastic large‐cell lymphoma |
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