Versatile effects of bacterium-released membrane vesicles on mammalian cells and infectious/inflammatory diseases

Gram-negative bacterium-released outer-membrane vesicles (OMVs) and Gram-positive bacterium-released membrane vesicles (MVs) share significant similarities with mammalian cell-derived MVs ( eg , microvesicles and exosomes) in terms of structure and their biological activities. Recent studies have re...

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Veröffentlicht in:	Acta pharmacologica Sinica 2018-04, Vol.39 (4), p.514-533
Hauptverfasser:	Yu, You-jiang, Wang, Xiao-hong, Fan, Guo-Chang
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Antigens Bacteria - metabolism Biomedical and Life Sciences Biomedicine Cell adhesion Cell adhesion & migration Cell adhesion molecules Cell injury Communicable Diseases - physiopathology Communicable Diseases - therapy Dendritic Cells - metabolism Deoxyribonucleic acid DNA Drug delivery Endothelial cells Epithelial cells Exosomes Extracellular Vesicles - chemistry Extracellular Vesicles - immunology Extracellular Vesicles - metabolism Extracellular Vesicles - microbiology Humans Immunogenicity Immunology Inflammation - physiopathology Inflammatory diseases Internal Medicine Intestine Mammalian cells Medical Microbiology Membrane vesicles Phagocytes - metabolism Pharmacology/Toxicology Proteins Review review-article Vaccine Vaccines, Acellular - therapeutic use Vesicles Virulence factors
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