Failure of physiologic transformation of spiral arteries, endothelial and trophoblast cell activation, and acute atherosis in the basal plate of the placenta

Background Failure of physiologic transformation of spiral arteries has been reported in preeclampsia, fetal growth restriction, fetal death, and spontaneous preterm labor with intact or ruptured membranes. Spiral arteries with failure of physiologic transformation are prone to develop atherosclerot...

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Veröffentlicht in:	American journal of obstetrics and gynecology 2017-03, Vol.216 (3), p.287.e1-287.e16
Hauptverfasser:	Labarrere, Carlos A., MD, DiCarlo, Hector L., MD, Bammerlin, Elaine, MA, Hardin, James W., PhD, Kim, Yeon M., MD, Chaemsaithong, Piya, MD, Haas, David M., MD, MS, Kassab, Ghassan S., PhD, Romero, Roberto, MD, DMedSci
Format:	Artikel
Sprache:	eng
Schlagworte:	acute atherosis Acute Disease Arteries - physiopathology Cross-Sectional Studies endothelial activation Endothelium, Vascular - physiopathology failure of physiologic transformation Female Humans ICAM-1 Obstetrics and Gynecology Placenta - blood supply Placenta - physiopathology placental basal plate Pregnancy Pregnancy Complications, Cardiovascular - pathology spiral arteries trophoblast activation Trophoblasts - cytology Vascular Diseases - pathology
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