A Detailed Model of Electroenzymatic Glutamate Biosensors To Aid in Sensor Optimization and in Applications in Vivo

Simulations conducted with a detailed model of glutamate biosensor performance describe the observed sensor performance well, illustrate the limits of sensor performance, and suggest a path toward sensor optimization. Glutamate is the most important excitatory neurotransmitter in the brain, and elec...

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Veröffentlicht in:	ACS chemical neuroscience 2018-02, Vol.9 (2), p.241-251
Hauptverfasser:	Clay, Mackenzie, Monbouquette, Harold G
Format:	Artikel
Sprache:	eng
Schlagworte:	Biosensing Techniques - instrumentation Computer Simulation Enzymes, Immobilized - chemistry Equipment Design Glutamic Acid - chemistry Hydrogen Peroxide - chemistry Kinetics Models, Theoretical Oxidoreductases - chemistry Oxygen - chemistry Polymers - chemistry
Online-Zugang:	Volltext
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