TrkB-Target Galectin-1 Impairs Immune Activation and Radiation Responses in Neuroblastoma: Implications for Tumour Therapy

Galectin-1 (Gal-1) has been described to promote tumour growth by inducing angiogenesis and to contribute to the tumour immune escape. We had previously identified up-regulation of Gal-1 in preclinical models of aggressive neuroblastoma (NB), the most common extracranial tumour of childhood. While G...

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Veröffentlicht in:	International journal of molecular sciences 2018-03, Vol.19 (3), p.718
Hauptverfasser:	Batzke, Katharina, Büchel, Gabriele, Hansen, Wiebke, Schramm, Alexander
Format:	Artikel
Sprache:	eng
Schlagworte:	Angiogenesis Children Galectin-1 Immune response Immune system Neuroblastoma Paracrine signalling Radiation therapy Radiation tolerance Review TrkB receptors Tumors
Online-Zugang:	Volltext
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