Upregulation of B7-H4 promotes tumor progression of intrahepatic cholangiocarcinoma

Recent reports show that B7-H4 is highly expressed in a variety of tumor cells, functions as a negative regulator of T cells and then promotes tumor progression. However, its expression and role in intrahepatic cholangiocarcinoma (ICC) remain unclear. In present study, B7-H4 expression in ICC and pe...

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Veröffentlicht in:	Cell death & disease 2017-12, Vol.8 (12), p.3205-13, Article 3205
Hauptverfasser:	Xie, Nan, Cai, Jia-Bin, Zhang, Lu, Zhang, Peng-Fei, Shen, Ying-Hao, Yang, Xuan, Lu, Jia-Cheng, Gao, Dong-Mei, Kang, Qiang, Liu, Li-Xin, Zhang, Chi, Huang, Xiao-Yong, Zou, Hao, Zhang, Xin-Yu, Song, Zheng-Ji, Sun, Hai-Xiang, Fu, Bi-Mang, Ke, Ai-Wu, Shi, Guo-Ming
Format:	Artikel
Sprache:	eng
Schlagworte:	Antibodies B7 antigen Bax protein Bcl-2 protein Biochemistry Biological activity Biomedical and Life Sciences Caspase Caspase-3 Cell Biology Cell Culture Cholangiocarcinoma Gene expression Immunology Life Sciences Lymph nodes Lymphocytes T Mesenchyme Metastases Metastasis mRNA Tumor cells
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