A Polysaccharide from Amusium Pleuronectes Combined with Praziquantel Treatment Ameliorates Hepatic Fibrosis in Schistosoma Japonicum-Infected Mice

BACKGROUND Polysaccharides from bivalves have multiple bioactivities in various aspects of biology. However, the role of a polysaccharide derived from Amusium pleuronectes on potential hepatoprotective effects remains unclear. MATERIAL AND METHODS A water-soluble polysaccharide was isolated from Amu...

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Veröffentlicht in:	Medical science monitor 2018-03, Vol.24, p.1597-1603
Hauptverfasser:	Tang, Xiaoniu, Hu, Wei, Lv, Yechao, Zhang, Wenqi, Sun, Tian, Jiang, Yuxin, Zhan, Xiaodong, Zhou, Shulin
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Bivalvia - chemistry Cytokines - blood Hyaluronoglucosaminidase - blood Interleukin-13 - metabolism Lab/In Vitro Research Liver Cirrhosis - drug therapy Liver Cirrhosis - pathology Male Mice, Inbred BALB C Molecular Weight Polysaccharides - isolation & purification Polysaccharides - pharmacology Polysaccharides - therapeutic use Praziquantel - pharmacology Praziquantel - therapeutic use Schistosoma japonicum - physiology Schistosomiasis - drug therapy Superoxide Dismutase - blood
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