High expression of hnRNPA1 promotes cell invasion by inducing EMT in gastric cancer

Advanced gastric cancer (GC) has a poor prognosis and its treatment strategies are not very efficient. Heterogeneous nuclear ribonucleoprotein A1 (hnRNPA1) has emerged as a plausible GC marker, however the role and molecular mechanism of hnRNPA1 in cell invasion and migration remains unknown. In the...

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Veröffentlicht in:	Oncology reports 2018-04, Vol.39 (4), p.1693-1701
Hauptverfasser:	Chen, Yahua, Liu, Jun, Wang, Wei, Xiang, Li, Wang, Jide, Liu, Side, Zhou, Hongyan, Guo, Zheng
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Biomarkers, Tumor - genetics Cancer therapies Carcinogenesis - genetics Care and treatment Cell cycle Cell growth Cell Line, Tumor Cell Movement - genetics Cell Proliferation - genetics Development and progression Epithelial-Mesenchymal Transition - genetics Female Gastric cancer Gene expression Gene Expression Regulation, Neoplastic Genetic aspects Health aspects Heterogeneous Nuclear Ribonucleoprotein A1 - genetics Humans Localization Male Medical prognosis Metastasis Mice Neoplasm Invasiveness - genetics Neoplasm Invasiveness - pathology Oncogenes Proteins Ribonucleoproteins Stomach cancer Stomach Neoplasms - genetics Stomach Neoplasms - pathology Studies Tumors Xenograft Model Antitumor Assays
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