The price of flexibility – a case study on septanoses as pyranose mimetics† †Electronic supplementary information (ESI) available. See DOI: 10.1039/c7sc04289b

Interacting with lectins, mannose can be mimicked with seven-membered ring analogues but at the price of a substantial entropy penalty. Seven-membered ring mimetics of mannose were studied as ligands for the mannose-specific bacterial lectin FimH, which plays an essential role in the first step of u...

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Veröffentlicht in:	Chemical science (Cambridge) 2017-11, Vol.9 (3), p.646-654
Hauptverfasser:	Sager, Christoph P., Fiege, Brigitte, Zihlmann, Pascal, Vannam, Raghu, Rabbani, Said, Jakob, Roman P., Preston, Roland C., Zalewski, Adam, Maier, Timm, Peczuh, Mark W., Ernst, Beat
Format:	Artikel
Sprache:	eng
Schlagworte:	Chemistry
Online-Zugang:	Volltext
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