Biomaterials‐Based Approaches to Tumor Spheroid and Organoid Modeling

Evolving understanding of structural and biological complexity of tumors has stimulated development of physiologically relevant tumor models for cancer research and drug discovery. A major motivation for developing new tumor models is to recreate the 3D environment of tumors and context‐mediated fun...

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Veröffentlicht in:	Advanced healthcare materials 2018-03, Vol.7 (6), p.e1700980-n/a
Hauptverfasser:	Thakuri, Pradip Shahi, Liu, Chun, Luker, Gary D., Tavana, Hossein
Format:	Artikel
Sprache:	eng
Schlagworte:	3D tumor models Biocompatible Materials - chemistry Biocompatible Materials - therapeutic use Biological evolution Biomaterials Biomedical materials Cancer Cell culture Drug discovery Drug Discovery - methods Embryogenesis Embryonic growth stage Humans Medical research Models, Biological Motivation natural materials Organoids Organoids - metabolism Organoids - pathology Precision medicine Precision Medicine - methods R&D Research & development Spheroids Spheroids, Cellular - metabolism Spheroids, Cellular - pathology synthetic materials Three dimensional models Tumors
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