Gene expression analysis: Regulation of key genes associated with mycophenolate mofetil treatment of symptomatic carotid artery stenosis

The present study analyzed gene expression arrays to identify differentially-expressed genes (DEGs) between mycophenolate mofetil (MMF)-treated and placebo-treated patients with symptomatic carotid artery stenosis (SCAS). In addition, the key genes involved in the pharmacology of MMF treatment in pa...

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Veröffentlicht in:	Molecular medicine reports 2017-11, Vol.16 (5), p.7450-7458
Hauptverfasser:	Jin, Feng, Wang, Kai, Sun, Xiaochuan, Zhang, Zhanpu, Han, Ping
Format:	Artikel
Sprache:	eng
Schlagworte:	Atherosclerosis Carotid arteries Carotid artery carotid artery stenosis Carotid Stenosis - drug therapy Carotid Stenosis - metabolism Carotid Stenosis - pathology Cell activation Cell adhesion & migration Cluster Analysis Computational Biology - methods Cytokines Databases, Genetic Gene expression Gene Expression Regulation Gene regulation genes Genomes Humans Kinases Lymphocytes T Metabolic pathways Mycophenolate mofetil Mycophenolic acid Mycophenolic Acid - therapeutic use Nitric oxide Online data bases pathway analysis Phosphorylation Principal Component Analysis Principal components analysis Protein interaction Protein Interaction Maps protein-protein interaction network Proteins RNA polymerase Sarcoma Software Stenosis Stroke Studies Transcription Transcription factors Tyrosine
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