Dysregulation of fibulin-5 and matrix metalloproteases in epithelial ovarian cancer

Fibulin 5 (FBLN5) is an extracellular matrix glycoprotein that suppresses matrix metalloprotease 9 (MMP-9), angiogenesis and epithelial cell motility. Here, we investigated the regulation and function of in epithelial ovarian cancer (EOC). FBLN5 mRNA was down-regulated 5-fold in EOC relative to beni...

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Veröffentlicht in:	Oncotarget 2018-03, Vol.9 (18), p.14251-14267
Hauptverfasser:	Manders, Dustin B, Kishore, Hari Annavarapu, Gazdar, Adi F, Keller, Patrick W, Tsunezumi, Jun, Yanagisawa, Hiromi, Lea, Jayanthi, Word, Ruth Ann
Format:	Artikel
Sprache:	eng
Schlagworte:	Research Paper
Online-Zugang:	Volltext
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