The KSEA App: a web-based tool for kinase activity inference from quantitative phosphoproteomics

Computational characterization of differential kinase activity from phosphoproteomics datasets is critical for correctly inferring cellular circuitry and how signaling cascades are altered in drug treatment and/or disease. Kinase-Substrate Enrichment Analysis (KSEA) offers a powerful approach to est...

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Veröffentlicht in:	Bioinformatics (Oxford, England) England), 2017-11, Vol.33 (21), p.3489-3491
Hauptverfasser:	Wiredja, Danica D, Koyutürk, Mehmet, Chance, Mark R
Format:	Artikel
Sprache:	eng
Schlagworte:	algorithms Applications Notes bioinformatics computer software data collection drug therapy enzyme activity enzymes Internet phosphorylation proteomics
Online-Zugang:	Volltext
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