Overexpressed circPVT1, a potential new circular RNA biomarker, contributes to doxorubicin and cisplatin resistance of osteosarcoma cells by regulating ABCB1

Circular RNAs (circRNAs) represent a widespread class of non-coding RNAs generated from back-splicing, with a circular loop structure. Many circRNAs have been reported to play essential roles in cancer development and have the potential to serve as a novel class of biomarkers for clinical diagnosis....

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Veröffentlicht in:	International journal of biological sciences 2018-01, Vol.14 (3), p.321-330
Hauptverfasser:	Kun Peng, Zhu, Long, Xiao, Chun Lin, Zhang
Format:	Artikel
Sprache:	eng
Schlagworte:	Alkaline phosphatase Biocompatibility Biomarkers Bone cancer Cancer Circular RNA Circularity Cisplatin Diagnosis Diagnostic systems Doxorubicin Drug resistance Gastric cancer Gene expression Osteosarcoma Osteosarcoma cells Research Paper Ribonucleic acid RNA Serum siRNA Splicing
Online-Zugang:	Volltext
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