Effectiveness of evidence-based treatments of fetal alcohol spectrum disorders in children and adolescents: a systematic review protocol
IntroductionThe aim of this paper is to provide a protocol for a systematic review assessing the effectiveness of evidence from randomised controlled trials comparing fetal alcohol spectrum disorders pharmacological and non-pharmacological interventions with placebo/dummy interventions or usual stan...
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| Veröffentlicht in: | BMJ open 2018-03, Vol.8 (3), p.e013775-e013775 |
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| creator | Singal, Deepa Menard, Chantalle Neilson, Christine J Brownell, Marni Hanlon-Dearman, Ana Chudley, Albert Zarychanski, Ryan Abou-Setta, Ahmed |
| description | IntroductionThe aim of this paper is to provide a protocol for a systematic review assessing the effectiveness of evidence from randomised controlled trials comparing fetal alcohol spectrum disorders pharmacological and non-pharmacological interventions with placebo/dummy interventions or usual standards of care in children and adolescents ( |
| doi_str_mv | 10.1136/bmjopen-2016-013775 |
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We will also search the reference lists of relevant articles and conference proceedings. Two reviewers will independently assess each study against predetermined inclusion/exclusion criteria and extract data including population characteristics, types and duration of interventions and outcomes from included trials. Internal validity will be assessed using the Cochrane Risk of Bias Tool. Primary outcome measures will be improvements in symptoms, including: hyperactivity, impulsivity and attention as measured by standard rating scales. Secondary outcome measures will include improvements in physical and mental health domains, as well as cognitive, behavioural, social and educational skills as measured by rating scales, standardised psychometric tests of IQ and memory, grade repetition, literacy tests and diagnosis of mental health disorder.Ethics and disseminationEthical approval will not be obtained since it is not required for systematic reviews as there are no concerns regarding patient privacy. The results of this review will be disseminated through publication in a peer-review journal and presented at relevant conferences.PROSPERO registration number CRD42013005996.</description><identifier>ISSN: 2044-6055</identifier><identifier>EISSN: 2044-6055</identifier><identifier>DOI: 10.1136/bmjopen-2016-013775</identifier><identifier>PMID: 29525767</identifier><language>eng</language><publisher>England: BMJ Publishing Group LTD</publisher><subject>Adolescent ; Antidepressants ; Attention deficit hyperactivity disorder ; Bias ; Child ; Childrens health ; Collaboration ; Comorbidity ; Evidence-based medicine ; Evidence-Based Practice ; Female ; Fetal Alcohol Spectrum Disorders - psychology ; Fetal Alcohol Spectrum Disorders - therapy ; Fetal alcohol syndrome ; Health Status ; Humans ; Hyperactivity ; Impulsivity ; Intellectual disabilities ; Male ; Medical research ; Neurodevelopmental Disorders - etiology ; Paediatrics ; Pregnancy ; Psychometrics ; Research Design ; Systematic review ; Systematic Reviews as Topic ; Teenagers</subject><ispartof>BMJ open, 2018-03, Vol.8 (3), p.e013775-e013775</ispartof><rights>Article author(s) (or their employer(s) unless otherwise stated in the text of the article) 2018. All rights reserved. No commercial use is permitted unless otherwise expressly granted.</rights><rights>2018 Article author(s) (or their employer(s) unless otherwise stated in the text of the article) 2018. All rights reserved. No commercial use is permitted unless otherwise expressly granted. This is an Open Access article distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/ Notwithstanding the ProQuest Terms and Conditions, you may use this content in accordance with the terms of the License.</rights><rights>Article author(s) (or their employer(s) unless otherwise stated in the text of the article) 2018. All rights reserved. No commercial use is permitted unless otherwise expressly granted. 2018</rights><lds50>peer_reviewed</lds50><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-b472t-d5055aea65e371c40d1e2a074c43efbe36389df8e498964f0f325a4c79834e793</citedby><cites>FETCH-LOGICAL-b472t-d5055aea65e371c40d1e2a074c43efbe36389df8e498964f0f325a4c79834e793</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://bmjopen.bmj.com/content/8/3/e013775.full.pdf$$EPDF$$P50$$Gbmj$$Hfree_for_read</linktopdf><linktohtml>$$Uhttps://bmjopen.bmj.com/content/8/3/e013775.full$$EHTML$$P50$$Gbmj$$Hfree_for_read</linktohtml><link.rule.ids>230,314,727,780,784,864,885,27549,27550,27924,27925,53791,53793,77601,77632</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/29525767$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Singal, Deepa</creatorcontrib><creatorcontrib>Menard, Chantalle</creatorcontrib><creatorcontrib>Neilson, Christine J</creatorcontrib><creatorcontrib>Brownell, Marni</creatorcontrib><creatorcontrib>Hanlon-Dearman, Ana</creatorcontrib><creatorcontrib>Chudley, Albert</creatorcontrib><creatorcontrib>Zarychanski, Ryan</creatorcontrib><creatorcontrib>Abou-Setta, Ahmed</creatorcontrib><title>Effectiveness of evidence-based treatments of fetal alcohol spectrum disorders in children and adolescents: a systematic review protocol</title><title>BMJ open</title><addtitle>BMJ Open</addtitle><description>IntroductionThe aim of this paper is to provide a protocol for a systematic review assessing the effectiveness of evidence from randomised controlled trials comparing fetal alcohol spectrum disorders pharmacological and non-pharmacological interventions with placebo/dummy interventions or usual standards of care in children and adolescents (<18 years old).Methods and analysisThe following electronic databases will be searched: Medline (Ovid), Cumulative Index of Nursing and Allied Health Plus with Full text (EBSCO), Cochrane Central Register of Controlled Trials (Cochrane Library—Wiley), PsycINFO (ProQuest) and Proquest DissertationsandTheses will be searched from inception to March 2017 for relevant citations of published trials using individualised search strategies prepared for database. We will also search the reference lists of relevant articles and conference proceedings. Two reviewers will independently assess each study against predetermined inclusion/exclusion criteria and extract data including population characteristics, types and duration of interventions and outcomes from included trials. Internal validity will be assessed using the Cochrane Risk of Bias Tool. Primary outcome measures will be improvements in symptoms, including: hyperactivity, impulsivity and attention as measured by standard rating scales. Secondary outcome measures will include improvements in physical and mental health domains, as well as cognitive, behavioural, social and educational skills as measured by rating scales, standardised psychometric tests of IQ and memory, grade repetition, literacy tests and diagnosis of mental health disorder.Ethics and disseminationEthical approval will not be obtained since it is not required for systematic reviews as there are no concerns regarding patient privacy. 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Academic</collection><collection>PubMed Central (Full Participant titles)</collection><jtitle>BMJ open</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Singal, Deepa</au><au>Menard, Chantalle</au><au>Neilson, Christine J</au><au>Brownell, Marni</au><au>Hanlon-Dearman, Ana</au><au>Chudley, Albert</au><au>Zarychanski, Ryan</au><au>Abou-Setta, Ahmed</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Effectiveness of evidence-based treatments of fetal alcohol spectrum disorders in children and adolescents: a systematic review protocol</atitle><jtitle>BMJ open</jtitle><addtitle>BMJ Open</addtitle><date>2018-03-01</date><risdate>2018</risdate><volume>8</volume><issue>3</issue><spage>e013775</spage><epage>e013775</epage><pages>e013775-e013775</pages><issn>2044-6055</issn><eissn>2044-6055</eissn><abstract>IntroductionThe aim of this paper is to provide a protocol for a systematic review assessing the effectiveness of evidence from randomised controlled trials comparing fetal alcohol spectrum disorders pharmacological and non-pharmacological interventions with placebo/dummy interventions or usual standards of care in children and adolescents (<18 years old).Methods and analysisThe following electronic databases will be searched: Medline (Ovid), Cumulative Index of Nursing and Allied Health Plus with Full text (EBSCO), Cochrane Central Register of Controlled Trials (Cochrane Library—Wiley), PsycINFO (ProQuest) and Proquest DissertationsandTheses will be searched from inception to March 2017 for relevant citations of published trials using individualised search strategies prepared for database. We will also search the reference lists of relevant articles and conference proceedings. Two reviewers will independently assess each study against predetermined inclusion/exclusion criteria and extract data including population characteristics, types and duration of interventions and outcomes from included trials. Internal validity will be assessed using the Cochrane Risk of Bias Tool. Primary outcome measures will be improvements in symptoms, including: hyperactivity, impulsivity and attention as measured by standard rating scales. Secondary outcome measures will include improvements in physical and mental health domains, as well as cognitive, behavioural, social and educational skills as measured by rating scales, standardised psychometric tests of IQ and memory, grade repetition, literacy tests and diagnosis of mental health disorder.Ethics and disseminationEthical approval will not be obtained since it is not required for systematic reviews as there are no concerns regarding patient privacy. The results of this review will be disseminated through publication in a peer-review journal and presented at relevant conferences.PROSPERO registration number CRD42013005996.</abstract><cop>England</cop><pub>BMJ Publishing Group LTD</pub><pmid>29525767</pmid><doi>10.1136/bmjopen-2016-013775</doi><oa>free_for_read</oa></addata></record> |
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| subjects | Adolescent Antidepressants Attention deficit hyperactivity disorder Bias Child Childrens health Collaboration Comorbidity Evidence-based medicine Evidence-Based Practice Female Fetal Alcohol Spectrum Disorders - psychology Fetal Alcohol Spectrum Disorders - therapy Fetal alcohol syndrome Health Status Humans Hyperactivity Impulsivity Intellectual disabilities Male Medical research Neurodevelopmental Disorders - etiology Paediatrics Pregnancy Psychometrics Research Design Systematic review Systematic Reviews as Topic Teenagers |
| title | Effectiveness of evidence-based treatments of fetal alcohol spectrum disorders in children and adolescents: a systematic review protocol |
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