Dorsal Hippocampus Drives Context-Induced Cocaine Seeking via Inputs to Lateral Septum

Lateral septum (LS) has re-emerged as an important structure in reward and addiction; however, LS afferents that drive addiction behaviors are unknown. Here, we used a modified self-administration/reinstatement procedure combined with anatomical, pharmacological, and chemogenetic techniques to chara...

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Veröffentlicht in:	Neuropsychopharmacology (New York, N.Y.) N.Y.), 2018-04, Vol.43 (5), p.987-1000
Hauptverfasser:	McGlinchey, Ellen M, Aston-Jones, Gary
Format:	Artikel
Sprache:	eng
Schlagworte:	Addictions Animals Baclofen - pharmacology Behavior, Addictive Clozapine - analogs & derivatives Clozapine - pharmacology Cocaine Cocaine - pharmacology Cues Drug abuse Drug self-administration Drug-Seeking Behavior - drug effects Drug-Seeking Behavior - physiology Extinction, Psychological - drug effects Hippocampus Hippocampus - drug effects Hippocampus - physiology Inactivation Locomotion - drug effects Male Microinjections Muscimol - pharmacology Narcotics Neuroanatomical Tract-Tracing Techniques Oncogene Proteins v-fos - metabolism Original Rats Reinforcement Reinstatement Self Administration Septal Nuclei - drug effects Septal Nuclei - physiology Septum
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