Considerations for the Full Global Withdrawal of Oral Polio Vaccine After Eradication of Polio

Eliminating the risk of polio from vaccine-derived polioviruses is essential for creating a polio-free world, and eliminating that risk will require stopping use of all oral polio vaccines (OPVs) once all types of wild polioviruses have been eradicated. In many ways, the experience with the global s...

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Veröffentlicht in:The Journal of infectious diseases 2017-07, Vol.216 (suppl_1), p.S217-S225
Hauptverfasser: Hampton, Lee M., du Châtellier, Gaël Maufras, Fournier-Caruana, Jacqueline, Ottosen, Ann, Rubin, Jennifer, Menning, Lisa, Farrell, Margaret, Shendale, Stephanie, Patel, Manish
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container_end_page S225
container_issue suppl_1
container_start_page S217
container_title The Journal of infectious diseases
container_volume 216
creator Hampton, Lee M.
du Châtellier, Gaël Maufras
Fournier-Caruana, Jacqueline
Ottosen, Ann
Rubin, Jennifer
Menning, Lisa
Farrell, Margaret
Shendale, Stephanie
Patel, Manish
description Eliminating the risk of polio from vaccine-derived polioviruses is essential for creating a polio-free world, and eliminating that risk will require stopping use of all oral polio vaccines (OPVs) once all types of wild polioviruses have been eradicated. In many ways, the experience with the global switch from trivalent OPV (tOPV) to bivalent OPV (bOPV) can inform the eventual full global withdrawal of OPV. Significant preparation will be needed for a thorough, synchronized, and full withdrawal of OPV, and such preparation would be aided by setting a reasonably firm date for OPV withdrawal as far in advance as possible, ideally at least 24 months. A shorter lead time would provide valuable flexibility for decisions about when to stop use of OPV in the context of uncertainty about whether or not all types of wild polioviruses had been eradicated, but it might increase the cost of OPV withdrawal.
doi_str_mv 10.1093/infdis/jix105
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source Jstor Complete Legacy; Oxford University Press Journals All Titles (1996-Current); MEDLINE; Alma/SFX Local Collection
subjects Disease Eradication
Disease Outbreaks - prevention & control
Global Health
Humans
IPV INTRODUCTION AND THE SWITCH
Poliomyelitis - prevention & control
Poliomyelitis - transmission
Poliomyelitis - virology
Poliovirus Vaccine, Oral
Supplement
title Considerations for the Full Global Withdrawal of Oral Polio Vaccine After Eradication of Polio
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