Health-related quality of life in patients with polycystic ovary syndrome: validation of the German PCOSQ-G

Purpose Patients with polycystic ovary syndrome (PCOS) report a decreased health-related quality of life (HRQOL) and higher levels of psychological distress. Validated questionnaires are necessary to assess the impact of PCOS on patients’ lives. The aim of the present study was to evaluate the Germa...

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Veröffentlicht in:Archives of gynecology and obstetrics 2018-04, Vol.297 (4), p.1027-1035
Hauptverfasser: Böttcher, B., Fessler, S., Friedl, F., Toth, B., Walter, M. H., Wildt, L., Riedl, D.
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container_end_page 1035
container_issue 4
container_start_page 1027
container_title Archives of gynecology and obstetrics
container_volume 297
creator Böttcher, B.
Fessler, S.
Friedl, F.
Toth, B.
Walter, M. H.
Wildt, L.
Riedl, D.
description Purpose Patients with polycystic ovary syndrome (PCOS) report a decreased health-related quality of life (HRQOL) and higher levels of psychological distress. Validated questionnaires are necessary to assess the impact of PCOS on patients’ lives. The aim of the present study was to evaluate the German “Polycystic Ovary Syndrome Questionnaire” (PCOSQ-G). Methods The psychometric properties of the PCOSQ-G were investigated in PCOS patients with item-total correlation, internal consistency and test–retest reliability. Correlations with the Short-Form-36 Health Survey (SF-36) and the Hospital Anxiety and Depression Scale (HADS-D) were calculated to evaluate the validity of the PCOSQ-G. Discriminatory validity was investigated through a receiver operating characteristic curve and independent sample t tests compared with healthy controls. Results Good psychometric properties were found for most items. Acceptable to high internal consistency was found for the total score ( α  = 0.94–0.95) and all subscales ( α  = 0.70–0.97). High test–retest reliability was found for the total score (0.86) and all subscales (0.81–0.90). The validity analyses showed that the PCOSQ-G total score was positively correlated with both SF-36 summary scales and was negatively correlated with both HADS subscales. Patients reported significantly lower values for the PCOSQ-G total score ( p  
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H. ; Wildt, L. ; Riedl, D.</creator><creatorcontrib>Böttcher, B. ; Fessler, S. ; Friedl, F. ; Toth, B. ; Walter, M. H. ; Wildt, L. ; Riedl, D.</creatorcontrib><description>Purpose Patients with polycystic ovary syndrome (PCOS) report a decreased health-related quality of life (HRQOL) and higher levels of psychological distress. Validated questionnaires are necessary to assess the impact of PCOS on patients’ lives. The aim of the present study was to evaluate the German “Polycystic Ovary Syndrome Questionnaire” (PCOSQ-G). Methods The psychometric properties of the PCOSQ-G were investigated in PCOS patients with item-total correlation, internal consistency and test–retest reliability. Correlations with the Short-Form-36 Health Survey (SF-36) and the Hospital Anxiety and Depression Scale (HADS-D) were calculated to evaluate the validity of the PCOSQ-G. Discriminatory validity was investigated through a receiver operating characteristic curve and independent sample t tests compared with healthy controls. Results Good psychometric properties were found for most items. Acceptable to high internal consistency was found for the total score ( α  = 0.94–0.95) and all subscales ( α  = 0.70–0.97). High test–retest reliability was found for the total score (0.86) and all subscales (0.81–0.90). The validity analyses showed that the PCOSQ-G total score was positively correlated with both SF-36 summary scales and was negatively correlated with both HADS subscales. Patients reported significantly lower values for the PCOSQ-G total score ( p  &lt; 0.001) and all subscales, and the PCOSQ-G discriminated well between patients and healthy controls (AUC = 0.81, p  &lt; 0.001). Conclusions PCOSQ-G is a reliable and valid tool to assess the HRQOL in patients with PCOS and can be used in future clinical research. Patients with PCOS exhibited an impaired HRQOL, which indicates the need for psychosomatic counseling.</description><identifier>ISSN: 0932-0067</identifier><identifier>ISSN: 1432-0711</identifier><identifier>EISSN: 1432-0711</identifier><identifier>DOI: 10.1007/s00404-017-4623-2</identifier><identifier>PMID: 29249009</identifier><language>eng</language><publisher>Berlin/Heidelberg: Springer Berlin Heidelberg</publisher><subject>Adolescent ; Adult ; Anxiety - diagnosis ; Anxiety - psychology ; Austria ; Case-Control Studies ; Depression - diagnosis ; Depression - psychology ; Endocrinology ; Female ; Gynecologic Endocrinology and Reproductive Medicine ; Gynecology ; Health Status ; Human Genetics ; Humans ; Medicine ; Medicine &amp; Public Health ; Middle Aged ; Obstetrics/Perinatology/Midwifery ; Polycystic ovary syndrome ; Polycystic Ovary Syndrome - diagnosis ; Polycystic Ovary Syndrome - psychology ; Psychiatric Status Rating Scales ; Psychometrics ; Quality of life ; Quality of Life - psychology ; Quantitative psychology ; Reproducibility of Results ; Surveys and Questionnaires ; Validity</subject><ispartof>Archives of gynecology and obstetrics, 2018-04, Vol.297 (4), p.1027-1035</ispartof><rights>The Author(s) 2017</rights><rights>Archives of Gynecology and Obstetrics is a copyright of Springer, (2017). All Rights Reserved. © 2017. This work is published under http://creativecommons.org/licenses/by/4.0/ (the “License”). Notwithstanding the ProQuest Terms and Conditions, you may use this content in accordance with the terms of the License.</rights><lds50>peer_reviewed</lds50><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c470t-20bb5a84bf2e6696016088181b2b1e8dd5c77948de68a8c00c6f6b3ca627236d3</citedby><cites>FETCH-LOGICAL-c470t-20bb5a84bf2e6696016088181b2b1e8dd5c77948de68a8c00c6f6b3ca627236d3</cites><orcidid>0000-0002-7745-9130 ; 0000-0003-0518-3144</orcidid></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://link.springer.com/content/pdf/10.1007/s00404-017-4623-2$$EPDF$$P50$$Gspringer$$Hfree_for_read</linktopdf><linktohtml>$$Uhttps://link.springer.com/10.1007/s00404-017-4623-2$$EHTML$$P50$$Gspringer$$Hfree_for_read</linktohtml><link.rule.ids>230,314,778,782,883,27911,27912,41475,42544,51306</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/29249009$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Böttcher, B.</creatorcontrib><creatorcontrib>Fessler, S.</creatorcontrib><creatorcontrib>Friedl, F.</creatorcontrib><creatorcontrib>Toth, B.</creatorcontrib><creatorcontrib>Walter, M. H.</creatorcontrib><creatorcontrib>Wildt, L.</creatorcontrib><creatorcontrib>Riedl, D.</creatorcontrib><title>Health-related quality of life in patients with polycystic ovary syndrome: validation of the German PCOSQ-G</title><title>Archives of gynecology and obstetrics</title><addtitle>Arch Gynecol Obstet</addtitle><addtitle>Arch Gynecol Obstet</addtitle><description>Purpose Patients with polycystic ovary syndrome (PCOS) report a decreased health-related quality of life (HRQOL) and higher levels of psychological distress. Validated questionnaires are necessary to assess the impact of PCOS on patients’ lives. The aim of the present study was to evaluate the German “Polycystic Ovary Syndrome Questionnaire” (PCOSQ-G). Methods The psychometric properties of the PCOSQ-G were investigated in PCOS patients with item-total correlation, internal consistency and test–retest reliability. Correlations with the Short-Form-36 Health Survey (SF-36) and the Hospital Anxiety and Depression Scale (HADS-D) were calculated to evaluate the validity of the PCOSQ-G. Discriminatory validity was investigated through a receiver operating characteristic curve and independent sample t tests compared with healthy controls. Results Good psychometric properties were found for most items. Acceptable to high internal consistency was found for the total score ( α  = 0.94–0.95) and all subscales ( α  = 0.70–0.97). High test–retest reliability was found for the total score (0.86) and all subscales (0.81–0.90). The validity analyses showed that the PCOSQ-G total score was positively correlated with both SF-36 summary scales and was negatively correlated with both HADS subscales. Patients reported significantly lower values for the PCOSQ-G total score ( p  &lt; 0.001) and all subscales, and the PCOSQ-G discriminated well between patients and healthy controls (AUC = 0.81, p  &lt; 0.001). Conclusions PCOSQ-G is a reliable and valid tool to assess the HRQOL in patients with PCOS and can be used in future clinical research. Patients with PCOS exhibited an impaired HRQOL, which indicates the need for psychosomatic counseling.</description><subject>Adolescent</subject><subject>Adult</subject><subject>Anxiety - diagnosis</subject><subject>Anxiety - psychology</subject><subject>Austria</subject><subject>Case-Control Studies</subject><subject>Depression - diagnosis</subject><subject>Depression - psychology</subject><subject>Endocrinology</subject><subject>Female</subject><subject>Gynecologic Endocrinology and Reproductive Medicine</subject><subject>Gynecology</subject><subject>Health Status</subject><subject>Human Genetics</subject><subject>Humans</subject><subject>Medicine</subject><subject>Medicine &amp; Public Health</subject><subject>Middle Aged</subject><subject>Obstetrics/Perinatology/Midwifery</subject><subject>Polycystic ovary syndrome</subject><subject>Polycystic Ovary Syndrome - diagnosis</subject><subject>Polycystic Ovary Syndrome - psychology</subject><subject>Psychiatric Status Rating Scales</subject><subject>Psychometrics</subject><subject>Quality of life</subject><subject>Quality of Life - psychology</subject><subject>Quantitative psychology</subject><subject>Reproducibility of Results</subject><subject>Surveys and Questionnaires</subject><subject>Validity</subject><issn>0932-0067</issn><issn>1432-0711</issn><issn>1432-0711</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2018</creationdate><recordtype>article</recordtype><sourceid>C6C</sourceid><sourceid>EIF</sourceid><sourceid>ABUWG</sourceid><sourceid>AFKRA</sourceid><sourceid>BENPR</sourceid><sourceid>CCPQU</sourceid><recordid>eNp1kc1u1DAUhS1ERaeFB2CDLLFhY3rtJLbDAqkatVOkSgUBa8txnI5LEk9tZ1Devo6mlB-Jla90v3N8rg5Crym8pwDiLAKUUBKggpScFYQ9QytaFoyAoPQ5WkG9zMDFMTqJ8Q6AMin5C3TMalbWAPUK_biyuk9bEmyvk23x_aR7l2bsO9y7zmI34p1Ozo4p4p8ubfHO97OZY3IG-70OM47z2AY_2A94n6Vthv24yNPW4o0Ngx7x5_XN1y9k8xIddbqP9tXje4q-X158W1-R65vNp_X5NTGlgEQYNE2lZdl0zHJec6AcpKSSNqyhVrZtZYSoS9laLrU0AIZ3vCmM5kywgrfFKfp48N1NzWBbk8MH3atdcEMOrLx26u_N6Lbq1u9VJcuaVyIbvHs0CP5-sjGpwUVj-16P1k9R0VrIglFaVRl9-w9656cw5vMUY5xWBQixUPRAmeBjDLZ7CkNBLVWqQ5UqV6mWKhXLmjd_XvGk-NVdBtgBiHk13trw--v_uz4Arrup5w</recordid><startdate>20180401</startdate><enddate>20180401</enddate><creator>Böttcher, B.</creator><creator>Fessler, S.</creator><creator>Friedl, F.</creator><creator>Toth, B.</creator><creator>Walter, M. H.</creator><creator>Wildt, L.</creator><creator>Riedl, D.</creator><general>Springer Berlin Heidelberg</general><general>Springer Nature B.V</general><scope>C6C</scope><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>3V.</scope><scope>7X7</scope><scope>7XB</scope><scope>8FI</scope><scope>8FJ</scope><scope>8FK</scope><scope>ABUWG</scope><scope>AFKRA</scope><scope>BENPR</scope><scope>CCPQU</scope><scope>FYUFA</scope><scope>GHDGH</scope><scope>K9.</scope><scope>M0S</scope><scope>PQEST</scope><scope>PQQKQ</scope><scope>PQUKI</scope><scope>PRINS</scope><scope>7X8</scope><scope>5PM</scope><orcidid>https://orcid.org/0000-0002-7745-9130</orcidid><orcidid>https://orcid.org/0000-0003-0518-3144</orcidid></search><sort><creationdate>20180401</creationdate><title>Health-related quality of life in patients with polycystic ovary syndrome: validation of the German PCOSQ-G</title><author>Böttcher, B. ; Fessler, S. ; Friedl, F. ; Toth, B. ; Walter, M. H. ; Wildt, L. ; Riedl, D.</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c470t-20bb5a84bf2e6696016088181b2b1e8dd5c77948de68a8c00c6f6b3ca627236d3</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2018</creationdate><topic>Adolescent</topic><topic>Adult</topic><topic>Anxiety - diagnosis</topic><topic>Anxiety - psychology</topic><topic>Austria</topic><topic>Case-Control Studies</topic><topic>Depression - diagnosis</topic><topic>Depression - psychology</topic><topic>Endocrinology</topic><topic>Female</topic><topic>Gynecologic Endocrinology and Reproductive Medicine</topic><topic>Gynecology</topic><topic>Health Status</topic><topic>Human Genetics</topic><topic>Humans</topic><topic>Medicine</topic><topic>Medicine &amp; Public Health</topic><topic>Middle Aged</topic><topic>Obstetrics/Perinatology/Midwifery</topic><topic>Polycystic ovary syndrome</topic><topic>Polycystic Ovary Syndrome - diagnosis</topic><topic>Polycystic Ovary Syndrome - psychology</topic><topic>Psychiatric Status Rating Scales</topic><topic>Psychometrics</topic><topic>Quality of life</topic><topic>Quality of Life - psychology</topic><topic>Quantitative psychology</topic><topic>Reproducibility of Results</topic><topic>Surveys and Questionnaires</topic><topic>Validity</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Böttcher, B.</creatorcontrib><creatorcontrib>Fessler, S.</creatorcontrib><creatorcontrib>Friedl, F.</creatorcontrib><creatorcontrib>Toth, B.</creatorcontrib><creatorcontrib>Walter, M. 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H.</au><au>Wildt, L.</au><au>Riedl, D.</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Health-related quality of life in patients with polycystic ovary syndrome: validation of the German PCOSQ-G</atitle><jtitle>Archives of gynecology and obstetrics</jtitle><stitle>Arch Gynecol Obstet</stitle><addtitle>Arch Gynecol Obstet</addtitle><date>2018-04-01</date><risdate>2018</risdate><volume>297</volume><issue>4</issue><spage>1027</spage><epage>1035</epage><pages>1027-1035</pages><issn>0932-0067</issn><issn>1432-0711</issn><eissn>1432-0711</eissn><abstract>Purpose Patients with polycystic ovary syndrome (PCOS) report a decreased health-related quality of life (HRQOL) and higher levels of psychological distress. Validated questionnaires are necessary to assess the impact of PCOS on patients’ lives. The aim of the present study was to evaluate the German “Polycystic Ovary Syndrome Questionnaire” (PCOSQ-G). Methods The psychometric properties of the PCOSQ-G were investigated in PCOS patients with item-total correlation, internal consistency and test–retest reliability. Correlations with the Short-Form-36 Health Survey (SF-36) and the Hospital Anxiety and Depression Scale (HADS-D) were calculated to evaluate the validity of the PCOSQ-G. Discriminatory validity was investigated through a receiver operating characteristic curve and independent sample t tests compared with healthy controls. Results Good psychometric properties were found for most items. Acceptable to high internal consistency was found for the total score ( α  = 0.94–0.95) and all subscales ( α  = 0.70–0.97). High test–retest reliability was found for the total score (0.86) and all subscales (0.81–0.90). The validity analyses showed that the PCOSQ-G total score was positively correlated with both SF-36 summary scales and was negatively correlated with both HADS subscales. Patients reported significantly lower values for the PCOSQ-G total score ( p  &lt; 0.001) and all subscales, and the PCOSQ-G discriminated well between patients and healthy controls (AUC = 0.81, p  &lt; 0.001). Conclusions PCOSQ-G is a reliable and valid tool to assess the HRQOL in patients with PCOS and can be used in future clinical research. Patients with PCOS exhibited an impaired HRQOL, which indicates the need for psychosomatic counseling.</abstract><cop>Berlin/Heidelberg</cop><pub>Springer Berlin Heidelberg</pub><pmid>29249009</pmid><doi>10.1007/s00404-017-4623-2</doi><tpages>9</tpages><orcidid>https://orcid.org/0000-0002-7745-9130</orcidid><orcidid>https://orcid.org/0000-0003-0518-3144</orcidid><oa>free_for_read</oa></addata></record>
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source MEDLINE; Springer Nature - Complete Springer Journals
subjects Adolescent
Adult
Anxiety - diagnosis
Anxiety - psychology
Austria
Case-Control Studies
Depression - diagnosis
Depression - psychology
Endocrinology
Female
Gynecologic Endocrinology and Reproductive Medicine
Gynecology
Health Status
Human Genetics
Humans
Medicine
Medicine & Public Health
Middle Aged
Obstetrics/Perinatology/Midwifery
Polycystic ovary syndrome
Polycystic Ovary Syndrome - diagnosis
Polycystic Ovary Syndrome - psychology
Psychiatric Status Rating Scales
Psychometrics
Quality of life
Quality of Life - psychology
Quantitative psychology
Reproducibility of Results
Surveys and Questionnaires
Validity
title Health-related quality of life in patients with polycystic ovary syndrome: validation of the German PCOSQ-G
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