Health-related quality of life in patients with polycystic ovary syndrome: validation of the German PCOSQ-G
Purpose Patients with polycystic ovary syndrome (PCOS) report a decreased health-related quality of life (HRQOL) and higher levels of psychological distress. Validated questionnaires are necessary to assess the impact of PCOS on patients’ lives. The aim of the present study was to evaluate the Germa...
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Veröffentlicht in: | Archives of gynecology and obstetrics 2018-04, Vol.297 (4), p.1027-1035 |
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creator | Böttcher, B. Fessler, S. Friedl, F. Toth, B. Walter, M. H. Wildt, L. Riedl, D. |
description | Purpose
Patients with polycystic ovary syndrome (PCOS) report a decreased health-related quality of life (HRQOL) and higher levels of psychological distress. Validated questionnaires are necessary to assess the impact of PCOS on patients’ lives. The aim of the present study was to evaluate the German “Polycystic Ovary Syndrome Questionnaire” (PCOSQ-G).
Methods
The psychometric properties of the PCOSQ-G were investigated in PCOS patients with item-total correlation, internal consistency and test–retest reliability. Correlations with the Short-Form-36 Health Survey (SF-36) and the Hospital Anxiety and Depression Scale (HADS-D) were calculated to evaluate the validity of the PCOSQ-G. Discriminatory validity was investigated through a receiver operating characteristic curve and independent sample
t
tests compared with healthy controls.
Results
Good psychometric properties were found for most items. Acceptable to high internal consistency was found for the total score (
α
= 0.94–0.95) and all subscales (
α
= 0.70–0.97). High test–retest reliability was found for the total score (0.86) and all subscales (0.81–0.90). The validity analyses showed that the PCOSQ-G total score was positively correlated with both SF-36 summary scales and was negatively correlated with both HADS subscales. Patients reported significantly lower values for the PCOSQ-G total score (
p
|
doi_str_mv | 10.1007/s00404-017-4623-2 |
format | Article |
fullrecord | <record><control><sourceid>proquest_pubme</sourceid><recordid>TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_5849657</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><sourcerecordid>1978321155</sourcerecordid><originalsourceid>FETCH-LOGICAL-c470t-20bb5a84bf2e6696016088181b2b1e8dd5c77948de68a8c00c6f6b3ca627236d3</originalsourceid><addsrcrecordid>eNp1kc1u1DAUhS1ERaeFB2CDLLFhY3rtJLbDAqkatVOkSgUBa8txnI5LEk9tZ1Devo6mlB-Jla90v3N8rg5Crym8pwDiLAKUUBKggpScFYQ9QytaFoyAoPQ5WkG9zMDFMTqJ8Q6AMin5C3TMalbWAPUK_biyuk9bEmyvk23x_aR7l2bsO9y7zmI34p1Ozo4p4p8ubfHO97OZY3IG-70OM47z2AY_2A94n6Vthv24yNPW4o0Ngx7x5_XN1y9k8xIddbqP9tXje4q-X158W1-R65vNp_X5NTGlgEQYNE2lZdl0zHJec6AcpKSSNqyhVrZtZYSoS9laLrU0AIZ3vCmM5kywgrfFKfp48N1NzWBbk8MH3atdcEMOrLx26u_N6Lbq1u9VJcuaVyIbvHs0CP5-sjGpwUVj-16P1k9R0VrIglFaVRl9-w9656cw5vMUY5xWBQixUPRAmeBjDLZ7CkNBLVWqQ5UqV6mWKhXLmjd_XvGk-NVdBtgBiHk13trw--v_uz4Arrup5w</addsrcrecordid><sourcetype>Open Access Repository</sourcetype><iscdi>true</iscdi><recordtype>article</recordtype><pqid>2261530775</pqid></control><display><type>article</type><title>Health-related quality of life in patients with polycystic ovary syndrome: validation of the German PCOSQ-G</title><source>MEDLINE</source><source>Springer Nature - Complete Springer Journals</source><creator>Böttcher, B. ; Fessler, S. ; Friedl, F. ; Toth, B. ; Walter, M. H. ; Wildt, L. ; Riedl, D.</creator><creatorcontrib>Böttcher, B. ; Fessler, S. ; Friedl, F. ; Toth, B. ; Walter, M. H. ; Wildt, L. ; Riedl, D.</creatorcontrib><description>Purpose
Patients with polycystic ovary syndrome (PCOS) report a decreased health-related quality of life (HRQOL) and higher levels of psychological distress. Validated questionnaires are necessary to assess the impact of PCOS on patients’ lives. The aim of the present study was to evaluate the German “Polycystic Ovary Syndrome Questionnaire” (PCOSQ-G).
Methods
The psychometric properties of the PCOSQ-G were investigated in PCOS patients with item-total correlation, internal consistency and test–retest reliability. Correlations with the Short-Form-36 Health Survey (SF-36) and the Hospital Anxiety and Depression Scale (HADS-D) were calculated to evaluate the validity of the PCOSQ-G. Discriminatory validity was investigated through a receiver operating characteristic curve and independent sample
t
tests compared with healthy controls.
Results
Good psychometric properties were found for most items. Acceptable to high internal consistency was found for the total score (
α
= 0.94–0.95) and all subscales (
α
= 0.70–0.97). High test–retest reliability was found for the total score (0.86) and all subscales (0.81–0.90). The validity analyses showed that the PCOSQ-G total score was positively correlated with both SF-36 summary scales and was negatively correlated with both HADS subscales. Patients reported significantly lower values for the PCOSQ-G total score (
p
< 0.001) and all subscales, and the PCOSQ-G discriminated well between patients and healthy controls (AUC = 0.81,
p
< 0.001).
Conclusions
PCOSQ-G is a reliable and valid tool to assess the HRQOL in patients with PCOS and can be used in future clinical research. Patients with PCOS exhibited an impaired HRQOL, which indicates the need for psychosomatic counseling.</description><identifier>ISSN: 0932-0067</identifier><identifier>ISSN: 1432-0711</identifier><identifier>EISSN: 1432-0711</identifier><identifier>DOI: 10.1007/s00404-017-4623-2</identifier><identifier>PMID: 29249009</identifier><language>eng</language><publisher>Berlin/Heidelberg: Springer Berlin Heidelberg</publisher><subject>Adolescent ; Adult ; Anxiety - diagnosis ; Anxiety - psychology ; Austria ; Case-Control Studies ; Depression - diagnosis ; Depression - psychology ; Endocrinology ; Female ; Gynecologic Endocrinology and Reproductive Medicine ; Gynecology ; Health Status ; Human Genetics ; Humans ; Medicine ; Medicine & Public Health ; Middle Aged ; Obstetrics/Perinatology/Midwifery ; Polycystic ovary syndrome ; Polycystic Ovary Syndrome - diagnosis ; Polycystic Ovary Syndrome - psychology ; Psychiatric Status Rating Scales ; Psychometrics ; Quality of life ; Quality of Life - psychology ; Quantitative psychology ; Reproducibility of Results ; Surveys and Questionnaires ; Validity</subject><ispartof>Archives of gynecology and obstetrics, 2018-04, Vol.297 (4), p.1027-1035</ispartof><rights>The Author(s) 2017</rights><rights>Archives of Gynecology and Obstetrics is a copyright of Springer, (2017). All Rights Reserved. © 2017. This work is published under http://creativecommons.org/licenses/by/4.0/ (the “License”). Notwithstanding the ProQuest Terms and Conditions, you may use this content in accordance with the terms of the License.</rights><lds50>peer_reviewed</lds50><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c470t-20bb5a84bf2e6696016088181b2b1e8dd5c77948de68a8c00c6f6b3ca627236d3</citedby><cites>FETCH-LOGICAL-c470t-20bb5a84bf2e6696016088181b2b1e8dd5c77948de68a8c00c6f6b3ca627236d3</cites><orcidid>0000-0002-7745-9130 ; 0000-0003-0518-3144</orcidid></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://link.springer.com/content/pdf/10.1007/s00404-017-4623-2$$EPDF$$P50$$Gspringer$$Hfree_for_read</linktopdf><linktohtml>$$Uhttps://link.springer.com/10.1007/s00404-017-4623-2$$EHTML$$P50$$Gspringer$$Hfree_for_read</linktohtml><link.rule.ids>230,314,778,782,883,27911,27912,41475,42544,51306</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/29249009$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Böttcher, B.</creatorcontrib><creatorcontrib>Fessler, S.</creatorcontrib><creatorcontrib>Friedl, F.</creatorcontrib><creatorcontrib>Toth, B.</creatorcontrib><creatorcontrib>Walter, M. H.</creatorcontrib><creatorcontrib>Wildt, L.</creatorcontrib><creatorcontrib>Riedl, D.</creatorcontrib><title>Health-related quality of life in patients with polycystic ovary syndrome: validation of the German PCOSQ-G</title><title>Archives of gynecology and obstetrics</title><addtitle>Arch Gynecol Obstet</addtitle><addtitle>Arch Gynecol Obstet</addtitle><description>Purpose
Patients with polycystic ovary syndrome (PCOS) report a decreased health-related quality of life (HRQOL) and higher levels of psychological distress. Validated questionnaires are necessary to assess the impact of PCOS on patients’ lives. The aim of the present study was to evaluate the German “Polycystic Ovary Syndrome Questionnaire” (PCOSQ-G).
Methods
The psychometric properties of the PCOSQ-G were investigated in PCOS patients with item-total correlation, internal consistency and test–retest reliability. Correlations with the Short-Form-36 Health Survey (SF-36) and the Hospital Anxiety and Depression Scale (HADS-D) were calculated to evaluate the validity of the PCOSQ-G. Discriminatory validity was investigated through a receiver operating characteristic curve and independent sample
t
tests compared with healthy controls.
Results
Good psychometric properties were found for most items. Acceptable to high internal consistency was found for the total score (
α
= 0.94–0.95) and all subscales (
α
= 0.70–0.97). High test–retest reliability was found for the total score (0.86) and all subscales (0.81–0.90). The validity analyses showed that the PCOSQ-G total score was positively correlated with both SF-36 summary scales and was negatively correlated with both HADS subscales. Patients reported significantly lower values for the PCOSQ-G total score (
p
< 0.001) and all subscales, and the PCOSQ-G discriminated well between patients and healthy controls (AUC = 0.81,
p
< 0.001).
Conclusions
PCOSQ-G is a reliable and valid tool to assess the HRQOL in patients with PCOS and can be used in future clinical research. Patients with PCOS exhibited an impaired HRQOL, which indicates the need for psychosomatic counseling.</description><subject>Adolescent</subject><subject>Adult</subject><subject>Anxiety - diagnosis</subject><subject>Anxiety - psychology</subject><subject>Austria</subject><subject>Case-Control Studies</subject><subject>Depression - diagnosis</subject><subject>Depression - psychology</subject><subject>Endocrinology</subject><subject>Female</subject><subject>Gynecologic Endocrinology and Reproductive Medicine</subject><subject>Gynecology</subject><subject>Health Status</subject><subject>Human Genetics</subject><subject>Humans</subject><subject>Medicine</subject><subject>Medicine & Public Health</subject><subject>Middle Aged</subject><subject>Obstetrics/Perinatology/Midwifery</subject><subject>Polycystic ovary syndrome</subject><subject>Polycystic Ovary Syndrome - diagnosis</subject><subject>Polycystic Ovary Syndrome - psychology</subject><subject>Psychiatric Status Rating Scales</subject><subject>Psychometrics</subject><subject>Quality of life</subject><subject>Quality of Life - psychology</subject><subject>Quantitative psychology</subject><subject>Reproducibility of Results</subject><subject>Surveys and Questionnaires</subject><subject>Validity</subject><issn>0932-0067</issn><issn>1432-0711</issn><issn>1432-0711</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2018</creationdate><recordtype>article</recordtype><sourceid>C6C</sourceid><sourceid>EIF</sourceid><sourceid>ABUWG</sourceid><sourceid>AFKRA</sourceid><sourceid>BENPR</sourceid><sourceid>CCPQU</sourceid><recordid>eNp1kc1u1DAUhS1ERaeFB2CDLLFhY3rtJLbDAqkatVOkSgUBa8txnI5LEk9tZ1Devo6mlB-Jla90v3N8rg5Crym8pwDiLAKUUBKggpScFYQ9QytaFoyAoPQ5WkG9zMDFMTqJ8Q6AMin5C3TMalbWAPUK_biyuk9bEmyvk23x_aR7l2bsO9y7zmI34p1Ozo4p4p8ubfHO97OZY3IG-70OM47z2AY_2A94n6Vthv24yNPW4o0Ngx7x5_XN1y9k8xIddbqP9tXje4q-X158W1-R65vNp_X5NTGlgEQYNE2lZdl0zHJec6AcpKSSNqyhVrZtZYSoS9laLrU0AIZ3vCmM5kywgrfFKfp48N1NzWBbk8MH3atdcEMOrLx26u_N6Lbq1u9VJcuaVyIbvHs0CP5-sjGpwUVj-16P1k9R0VrIglFaVRl9-w9656cw5vMUY5xWBQixUPRAmeBjDLZ7CkNBLVWqQ5UqV6mWKhXLmjd_XvGk-NVdBtgBiHk13trw--v_uz4Arrup5w</recordid><startdate>20180401</startdate><enddate>20180401</enddate><creator>Böttcher, B.</creator><creator>Fessler, S.</creator><creator>Friedl, F.</creator><creator>Toth, B.</creator><creator>Walter, M. H.</creator><creator>Wildt, L.</creator><creator>Riedl, D.</creator><general>Springer Berlin Heidelberg</general><general>Springer Nature B.V</general><scope>C6C</scope><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>3V.</scope><scope>7X7</scope><scope>7XB</scope><scope>8FI</scope><scope>8FJ</scope><scope>8FK</scope><scope>ABUWG</scope><scope>AFKRA</scope><scope>BENPR</scope><scope>CCPQU</scope><scope>FYUFA</scope><scope>GHDGH</scope><scope>K9.</scope><scope>M0S</scope><scope>PQEST</scope><scope>PQQKQ</scope><scope>PQUKI</scope><scope>PRINS</scope><scope>7X8</scope><scope>5PM</scope><orcidid>https://orcid.org/0000-0002-7745-9130</orcidid><orcidid>https://orcid.org/0000-0003-0518-3144</orcidid></search><sort><creationdate>20180401</creationdate><title>Health-related quality of life in patients with polycystic ovary syndrome: validation of the German PCOSQ-G</title><author>Böttcher, B. ; Fessler, S. ; Friedl, F. ; Toth, B. ; Walter, M. H. ; Wildt, L. ; Riedl, D.</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c470t-20bb5a84bf2e6696016088181b2b1e8dd5c77948de68a8c00c6f6b3ca627236d3</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2018</creationdate><topic>Adolescent</topic><topic>Adult</topic><topic>Anxiety - diagnosis</topic><topic>Anxiety - psychology</topic><topic>Austria</topic><topic>Case-Control Studies</topic><topic>Depression - diagnosis</topic><topic>Depression - psychology</topic><topic>Endocrinology</topic><topic>Female</topic><topic>Gynecologic Endocrinology and Reproductive Medicine</topic><topic>Gynecology</topic><topic>Health Status</topic><topic>Human Genetics</topic><topic>Humans</topic><topic>Medicine</topic><topic>Medicine & Public Health</topic><topic>Middle Aged</topic><topic>Obstetrics/Perinatology/Midwifery</topic><topic>Polycystic ovary syndrome</topic><topic>Polycystic Ovary Syndrome - diagnosis</topic><topic>Polycystic Ovary Syndrome - psychology</topic><topic>Psychiatric Status Rating Scales</topic><topic>Psychometrics</topic><topic>Quality of life</topic><topic>Quality of Life - psychology</topic><topic>Quantitative psychology</topic><topic>Reproducibility of Results</topic><topic>Surveys and Questionnaires</topic><topic>Validity</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Böttcher, B.</creatorcontrib><creatorcontrib>Fessler, S.</creatorcontrib><creatorcontrib>Friedl, F.</creatorcontrib><creatorcontrib>Toth, B.</creatorcontrib><creatorcontrib>Walter, M. H.</creatorcontrib><creatorcontrib>Wildt, L.</creatorcontrib><creatorcontrib>Riedl, D.</creatorcontrib><collection>Springer Nature OA Free Journals</collection><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>ProQuest Central (Corporate)</collection><collection>Health & Medical Collection</collection><collection>ProQuest Central (purchase pre-March 2016)</collection><collection>Hospital Premium Collection</collection><collection>Hospital Premium Collection (Alumni Edition)</collection><collection>ProQuest Central (Alumni) (purchase pre-March 2016)</collection><collection>ProQuest Central (Alumni Edition)</collection><collection>ProQuest Central UK/Ireland</collection><collection>ProQuest Central</collection><collection>ProQuest One Community College</collection><collection>Health Research Premium Collection</collection><collection>Health Research Premium Collection (Alumni)</collection><collection>ProQuest Health & Medical Complete (Alumni)</collection><collection>Health & Medical Collection (Alumni Edition)</collection><collection>ProQuest One Academic Eastern Edition (DO NOT USE)</collection><collection>ProQuest One Academic</collection><collection>ProQuest One Academic UKI Edition</collection><collection>ProQuest Central China</collection><collection>MEDLINE - Academic</collection><collection>PubMed Central (Full Participant titles)</collection><jtitle>Archives of gynecology and obstetrics</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Böttcher, B.</au><au>Fessler, S.</au><au>Friedl, F.</au><au>Toth, B.</au><au>Walter, M. H.</au><au>Wildt, L.</au><au>Riedl, D.</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Health-related quality of life in patients with polycystic ovary syndrome: validation of the German PCOSQ-G</atitle><jtitle>Archives of gynecology and obstetrics</jtitle><stitle>Arch Gynecol Obstet</stitle><addtitle>Arch Gynecol Obstet</addtitle><date>2018-04-01</date><risdate>2018</risdate><volume>297</volume><issue>4</issue><spage>1027</spage><epage>1035</epage><pages>1027-1035</pages><issn>0932-0067</issn><issn>1432-0711</issn><eissn>1432-0711</eissn><abstract>Purpose
Patients with polycystic ovary syndrome (PCOS) report a decreased health-related quality of life (HRQOL) and higher levels of psychological distress. Validated questionnaires are necessary to assess the impact of PCOS on patients’ lives. The aim of the present study was to evaluate the German “Polycystic Ovary Syndrome Questionnaire” (PCOSQ-G).
Methods
The psychometric properties of the PCOSQ-G were investigated in PCOS patients with item-total correlation, internal consistency and test–retest reliability. Correlations with the Short-Form-36 Health Survey (SF-36) and the Hospital Anxiety and Depression Scale (HADS-D) were calculated to evaluate the validity of the PCOSQ-G. Discriminatory validity was investigated through a receiver operating characteristic curve and independent sample
t
tests compared with healthy controls.
Results
Good psychometric properties were found for most items. Acceptable to high internal consistency was found for the total score (
α
= 0.94–0.95) and all subscales (
α
= 0.70–0.97). High test–retest reliability was found for the total score (0.86) and all subscales (0.81–0.90). The validity analyses showed that the PCOSQ-G total score was positively correlated with both SF-36 summary scales and was negatively correlated with both HADS subscales. Patients reported significantly lower values for the PCOSQ-G total score (
p
< 0.001) and all subscales, and the PCOSQ-G discriminated well between patients and healthy controls (AUC = 0.81,
p
< 0.001).
Conclusions
PCOSQ-G is a reliable and valid tool to assess the HRQOL in patients with PCOS and can be used in future clinical research. Patients with PCOS exhibited an impaired HRQOL, which indicates the need for psychosomatic counseling.</abstract><cop>Berlin/Heidelberg</cop><pub>Springer Berlin Heidelberg</pub><pmid>29249009</pmid><doi>10.1007/s00404-017-4623-2</doi><tpages>9</tpages><orcidid>https://orcid.org/0000-0002-7745-9130</orcidid><orcidid>https://orcid.org/0000-0003-0518-3144</orcidid><oa>free_for_read</oa></addata></record> |
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source | MEDLINE; Springer Nature - Complete Springer Journals |
subjects | Adolescent Adult Anxiety - diagnosis Anxiety - psychology Austria Case-Control Studies Depression - diagnosis Depression - psychology Endocrinology Female Gynecologic Endocrinology and Reproductive Medicine Gynecology Health Status Human Genetics Humans Medicine Medicine & Public Health Middle Aged Obstetrics/Perinatology/Midwifery Polycystic ovary syndrome Polycystic Ovary Syndrome - diagnosis Polycystic Ovary Syndrome - psychology Psychiatric Status Rating Scales Psychometrics Quality of life Quality of Life - psychology Quantitative psychology Reproducibility of Results Surveys and Questionnaires Validity |
title | Health-related quality of life in patients with polycystic ovary syndrome: validation of the German PCOSQ-G |
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