More, less or both?
A 67-year-old Caucasian woman with no prior medical history was admitted to our hospital with complaints of generalised weakness, nausea, diarrhoea and weight loss. The patient suffered from tachycardia and hypotension. Blood tests revealed Graves’ thyrotoxicosis and the patient was treated accordin...
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| creator | Attaye, Ilias van Andel, Merel Kooter, Albertus Jozef |
| description | A 67-year-old Caucasian woman with no prior medical history was admitted to our hospital with complaints of generalised weakness, nausea, diarrhoea and weight loss. The patient suffered from tachycardia and hypotension. Blood tests revealed Graves’ thyrotoxicosis and the patient was treated accordingly. However, patient’s health continued to decline rapidly and further tests revealed a concomitant Addisonian crisis. Additional treatment with corticosteroids led to a full recovery. It is well known that autoimmune endocrine disorders tend to cluster. However, the presentation is usually sequential in time. This case reports the highly rare simultaneous presentation of Addison’s disease and Graves’ thyrotoxicosis. It also provides several suggestions to help establish the diagnoses. |
| doi_str_mv | 10.1136/bcr-2017-222355 |
| format | Article |
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The patient suffered from tachycardia and hypotension. Blood tests revealed Graves’ thyrotoxicosis and the patient was treated accordingly. However, patient’s health continued to decline rapidly and further tests revealed a concomitant Addisonian crisis. Additional treatment with corticosteroids led to a full recovery. It is well known that autoimmune endocrine disorders tend to cluster. However, the presentation is usually sequential in time. This case reports the highly rare simultaneous presentation of Addison’s disease and Graves’ thyrotoxicosis. It also provides several suggestions to help establish the diagnoses.</description><identifier>ISSN: 1757-790X</identifier><identifier>EISSN: 1757-790X</identifier><identifier>DOI: 10.1136/bcr-2017-222355</identifier><identifier>PMID: 29507013</identifier><language>eng</language><publisher>England: BMJ Publishing Group LTD</publisher><subject>Addison Disease - blood ; Addison Disease - complications ; Addison Disease - diagnosis ; Adrenal glands ; Adrenocorticotropic Hormone - blood ; Aged ; Autoimmune diseases ; Biomarkers - blood ; Blood tests ; Blood Urea Nitrogen ; Cardiac arrhythmia ; Case reports ; Creatinine - blood ; Endocrine disorders ; Female ; Graves Disease - complications ; Graves Disease - diagnosis ; Hospitals ; Humans ; Immunoglobulins ; Inflammatory bowel disease ; Internal medicine ; Kidney diseases ; Thyroid gland ; Thyrotoxicosis - complications ; Thyrotoxicosis - diagnosis ; Unusual Association of Diseases/Symptoms</subject><ispartof>BMJ case reports, 2018-03, Vol.2018, p.bcr-2017-222355</ispartof><rights>BMJ Publishing Group Ltd (unless otherwise stated in the text of the article) 2018. 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The patient suffered from tachycardia and hypotension. Blood tests revealed Graves’ thyrotoxicosis and the patient was treated accordingly. However, patient’s health continued to decline rapidly and further tests revealed a concomitant Addisonian crisis. Additional treatment with corticosteroids led to a full recovery. It is well known that autoimmune endocrine disorders tend to cluster. However, the presentation is usually sequential in time. This case reports the highly rare simultaneous presentation of Addison’s disease and Graves’ thyrotoxicosis. It also provides several suggestions to help establish the diagnoses.</description><subject>Addison Disease - blood</subject><subject>Addison Disease - complications</subject><subject>Addison Disease - diagnosis</subject><subject>Adrenal glands</subject><subject>Adrenocorticotropic Hormone - blood</subject><subject>Aged</subject><subject>Autoimmune diseases</subject><subject>Biomarkers - blood</subject><subject>Blood tests</subject><subject>Blood Urea Nitrogen</subject><subject>Cardiac arrhythmia</subject><subject>Case reports</subject><subject>Creatinine - blood</subject><subject>Endocrine disorders</subject><subject>Female</subject><subject>Graves Disease - complications</subject><subject>Graves Disease - diagnosis</subject><subject>Hospitals</subject><subject>Humans</subject><subject>Immunoglobulins</subject><subject>Inflammatory bowel disease</subject><subject>Internal medicine</subject><subject>Kidney diseases</subject><subject>Thyroid gland</subject><subject>Thyrotoxicosis - complications</subject><subject>Thyrotoxicosis - diagnosis</subject><subject>Unusual Association of Diseases/Symptoms</subject><issn>1757-790X</issn><issn>1757-790X</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2018</creationdate><recordtype>article</recordtype><sourceid>9YT</sourceid><sourceid>ACMMV</sourceid><sourceid>EIF</sourceid><sourceid>ABUWG</sourceid><sourceid>AFKRA</sourceid><sourceid>BENPR</sourceid><sourceid>CCPQU</sourceid><recordid>eNqFkE1LAzEQhoMottSePHiTghcR1-Zjs9lcFCl-QcWLgreQbGbtlt2mJl3Bf2_K1qJenEsG8szLzIPQEcEXhLBsbAqfUExEQillnO-gPhFcJELi190ffQ8NQ5jjWIykecr2UY9KjgUmrI8OH52H81ENIYycHxm3ml0doL1S1wGGm3eAXm5vnif3yfTp7mFyPU0Mo5wnlEhiQXKrM5ClLVhqCpNLBjnEbUrNDSMZUGsshlRKym1pueQ8t1wDKQo2QJdd7rI1DdgCFiuva7X0VaP9p3K6Ur9_FtVMvbkPxfNUSCJiwOkmwLv3FsJKNVUooK71AlwbVJRDaCZzRiN68gedu9Yv4nlrCmcsF4RHatxRhXcheCi3yxCs1s5VdL4eEKpzHieOf96w5b8NR-CsA0wz_zftC0uHh9M</recordid><startdate>20180305</startdate><enddate>20180305</enddate><creator>Attaye, Ilias</creator><creator>van Andel, Merel</creator><creator>Kooter, Albertus Jozef</creator><general>BMJ Publishing Group LTD</general><general>BMJ Publishing Group</general><scope>9YT</scope><scope>ACMMV</scope><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>3V.</scope><scope>7RV</scope><scope>7X7</scope><scope>7XB</scope><scope>88E</scope><scope>8FI</scope><scope>8FJ</scope><scope>8FK</scope><scope>ABUWG</scope><scope>AFKRA</scope><scope>BENPR</scope><scope>BTHHO</scope><scope>CCPQU</scope><scope>FYUFA</scope><scope>GHDGH</scope><scope>K9.</scope><scope>KB0</scope><scope>M0S</scope><scope>M1P</scope><scope>NAPCQ</scope><scope>PQEST</scope><scope>PQQKQ</scope><scope>PQUKI</scope><scope>PRINS</scope><scope>7X8</scope><scope>5PM</scope></search><sort><creationdate>20180305</creationdate><title>More, less or both?</title><author>Attaye, Ilias ; 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| source | MEDLINE; Elektronische Zeitschriftenbibliothek - Frei zugängliche E-Journals; PubMed Central |
| subjects | Addison Disease - blood Addison Disease - complications Addison Disease - diagnosis Adrenal glands Adrenocorticotropic Hormone - blood Aged Autoimmune diseases Biomarkers - blood Blood tests Blood Urea Nitrogen Cardiac arrhythmia Case reports Creatinine - blood Endocrine disorders Female Graves Disease - complications Graves Disease - diagnosis Hospitals Humans Immunoglobulins Inflammatory bowel disease Internal medicine Kidney diseases Thyroid gland Thyrotoxicosis - complications Thyrotoxicosis - diagnosis Unusual Association of Diseases/Symptoms |
| title | More, less or both? |
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