Clinical implications of bone marrow adiposity

Marrow adipocytes, collectively termed marrow adipose tissue (MAT), reside in the bone marrow in close contact to bone cells and haematopoietic cells. Marrow adipocytes arise from the mesenchymal stem cell and share their origin with the osteoblast. Shifts in the lineage allocation of the mesenchyma...

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Veröffentlicht in:	Journal of internal medicine 2018-02, Vol.283 (2), p.121-139
Hauptverfasser:	Veldhuis‐Vlug, A. G., Rosen, C. J.
Format:	Artikel
Sprache:	eng
Schlagworte:	Adipocytes Adipocytes - metabolism Adipocytes - physiology Adiponectin Adipose tissue Adiposity - physiology Aging - physiology Animals Anorexia Anorexia Nervosa - physiopathology Biocompatibility Biomedical materials Bone marrow Bone Marrow - metabolism Bone Marrow - physiology bone marrow adipocyte Bone remodeling bone remodelling Bone resorption Cell proliferation Chemotherapy Cytokines Diabetes mellitus Diseases Eating disorders Fatty acids Growth - physiology haematopoiesis Health risks Hematopoietic stem cells Humans Leukemia Lipolysis Menopause - physiology mesenchymal stem cell Mesenchyme Neoplasms - physiopathology Obesity - physiopathology Osteoporosis Osteoporosis - physiopathology Post-menopause Stem cell factor Stem cells TRANCE protein
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