Recurrent RET Gene Rearrangements in Intraductal Carcinomas of Salivary Gland

Intraductal carcinoma (IC) is the World Health Organization designation for lesions previously called low-grade cribriform cystadenocarcinoma. The relationship of IC to salivary duct carcinoma (SDC) is controversial, but currently these are considered distinct entities. It is hypothesized that IC an...

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Veröffentlicht in:	The American journal of surgical pathology 2018-04, Vol.42 (4), p.442-452
Hauptverfasser:	Weinreb, Ilan, Bishop, Justin A, Chiosea, Simion I, Seethala, Raja R, Perez-Ordonez, Bayardo, Zhang, Lei, Sung, Yun-Shao, Chen, Chun-Liang, Assaad, Adel, Oliai, Bahram R, Antonescu, Cristina R
Format:	Artikel
Sprache:	eng
Schlagworte:	Adult Aged Aged, 80 and over Biomarkers, Tumor - genetics Biopsy Carcinoma, Intraductal, Noninfiltrating - genetics Carcinoma, Intraductal, Noninfiltrating - pathology Cystadenocarcinoma - genetics Cystadenocarcinoma - pathology DNA Mutational Analysis Female Gene Fusion Gene Rearrangement Genetic Predisposition to Disease Humans In Situ Hybridization, Fluorescence Male Middle Aged Mutation Neoplasm Grading Phenotype Proto-Oncogene Proteins c-ret - genetics Salivary Gland Neoplasms - genetics Salivary Gland Neoplasms - pathology Sequence Analysis, RNA
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