Development of the Swimbladder Surfactant System and Biogenesis of Lysosome-Related Organelles Is Regulated by BLOS1 in Zebrafish

Hermansky-Pudlak syndrome (HPS) is a human autosomal recessive disorder that is characterized by oculocutaneous albinism and a deficiency of the platelet storage pool resulting from defective biogenesis of lysosome-related organelles (LROs). To date, 10 HPS genes have been identified, three of which...

Ausführliche Beschreibung

Gespeichert in:

Bibliographische Detailangaben
Veröffentlicht in:	Genetics (Austin) 2018-03, Vol.208 (3), p.1131-1146
Hauptverfasser:	Chen, Tianbing, Song, Guili, Yang, Huihui, Mao, Lin, Cui, Zongbin, Huang, Kaiyao
Format:	Artikel
Sprache:	eng
Schlagworte:	Air Sacs - metabolism Air Sacs - ultrastructure Albinism Animals Animals, Genetically Modified Biosynthesis Danio rerio Defects Evolution Eye Proteins - chemistry Eye Proteins - genetics Eye Proteins - metabolism Gene expression Gene Expression Regulation Genes Genetics Hereditary diseases Hermanski-Pudlak Syndrome - genetics Hermanski-Pudlak Syndrome - metabolism Hermansky-Pudlak syndrome Homeostasis Investigations Lethality Lungs Lysosomes - metabolism Lysosomes - ultrastructure Mammals Melanin Mutation Organelles Organelles - metabolism Organelles - ultrastructure Pathogenesis Phenotype Protein Subunits Proteins Surface-Active Agents - metabolism Surfactants Zebrafish Zebrafish - physiology
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!

Schreiben Sie den ersten Kommentar!