Coordinated transcription of ANRIL and P16 genes is silenced by P16 DNA methylation

To investigate the relationship between the transcription of , , and at the same locus and the regulation mechanism of . Publicly available database of Cancer Cell Line Encyclopedia (CCLE) was used in bioinformatic analyses. Methylation of CpG islands was detected by denaturing high performance liqu...

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Veröffentlicht in:Chinese journal of cancer research 2018-02, Vol.30 (1), p.93-103
Hauptverfasser: Gan, Ying, Ma, Wanru, Wang, Xiuhong, Qiao, Juanli, Zhang, Baozhen, Cui, Chenghua, Liu, Zhaojun, Deng, Dajun
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Sprache:eng
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