Matricellular CCN6 (WISP3) protein: a tumor suppressor for mammary metaplastic carcinomas

Located at 6q22–23, Ccn6 (WISP3) encodes for a matrix-associated protein of the CCN family, characterized by regulatory, rather than structural, roles in development and cancer. CCN6, the least studied member of the CCN family, shares the conserved multimodular structure of CCN proteins, as well as...

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Veröffentlicht in:	Journal of cell communication and signaling 2018-03, Vol.12 (1), p.13-19
Hauptverfasser:	Tran, Mai N., Kleer, Celina G.
Format:	Artikel
Sprache:	eng
Schlagworte:	Biomedical and Life Sciences Biomedicine Breast cancer Breast carcinoma CCN6 Cell Biology EMT Epithelial to mesenchymal Inflammation Invasiveness Knockout mouse Life Sciences Mammary gland Mesenchyme Metaplastic MMTV‐cre mRNA Proteins Review Spindle cell Stem cells Tumor suppressor genes WISP3
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