Novel TLR7 agonist stimulates activity of CIK/NK immunological effector cells to enhance antitumor cytotoxicity

Toll-like receptor (TLR) 7/8 agonists have been applied in combination with chemo-, radio- or immunotherapy for lymphoma, and used as topical drugs for the treatment of viral skin lesions and skin tumors. In the present study, the role of an adenine analog, 9-(4-carboxyphenyl)-8-hydroxy-2-(2-methoxy...

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Veröffentlicht in:	Oncology letters 2018-04, Vol.15 (4), p.5105-5110
Hauptverfasser:	Gao, Dong, Cai, Yongguang, Chen, Yanyuan, Li, Wang, Wei, Chih-Chang, Luo, Xiaoling, Wang, Yuhuan
Format:	Artikel
Sprache:	eng
Schlagworte:	Antigens Cancer Care and treatment Cell culture Chemotherapy Cytokines Cytotoxicity Health aspects Immunology Immunotherapy Ligands Lymphocytes Lymphoma Methods Oncology, Experimental Patient outcomes Pharmaceutical industry T cell receptors Toll-like receptors
Online-Zugang:	Volltext
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