Immunosenescence of microglia and macrophages: impact on the ageing central nervous system

Ageing of the central nervous system results in a loss of both grey and white matter, leading to cognitive decline. Additional injury to both the grey and white matter is documented in many neurological disorders with ageing, including Alzheimer's disease, traumatic brain and spinal cord injury...

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Veröffentlicht in:	Brain (London, England : 1878) England : 1878), 2016-03, Vol.139 (Pt 3), p.653-661
Hauptverfasser:	Rawji, Khalil S, Mishra, Manoj K, Michaels, Nathan J, Rivest, Serge, Stys, Peter K, Yong, V Wee
Format:	Artikel
Sprache:	eng
Schlagworte:	Aging - immunology Aging - pathology Animals Central Nervous System - immunology Central Nervous System - pathology Humans Immunosenescence - immunology Macrophages - immunology Macrophages - pathology Microglia - immunology Microglia - pathology Nervous System Diseases - diagnosis Nervous System Diseases - immunology Updates
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